Program in Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Braz Oral Res. 2012 Jul-Aug;26(4):355-9. doi: 10.1590/s1806-83242012005000011. Epub 2012 Jun 19.
This study investigated the viability of the cell block technique as an auxiliary method of diagnosing jawbone lesions. Thirty-three clinically diagnosed jawbone lesions with a cystic appearance were subjected to aspiration. The aspirated material was processed by the cell block technique, and the lesions were biopsied and treated. Cytological findings (cell block) and histopathology analyses (gold standard) were compared by the chi-square test. There were associations between cysts and cholesterol crystal clefts, between keratocystic odontogenic tumors (KOT) and epithelial cells, and between KOT and parakeratin. The occurrence of cholesterol crystal clefts in cell block slides was correlated with cystic lesions, and the parakeratin presence was a KOT indicator. The cell block technique proved to be fast, easy-to-handle, and low-cost, making it an attractive auxiliary method for the preliminary diagnosis of jawbone lesions.
本研究探讨了细胞块技术作为辅助诊断颌骨病变的一种方法的可行性。对 33 例临床诊断为囊性的颌骨病变进行了抽吸。将抽吸的材料进行细胞块技术处理，并对病变进行活检和处理。通过卡方检验比较细胞学发现（细胞块）和组织病理学分析（金标准）。囊肿与胆固醇结晶裂隙之间、角化囊肿型牙源性肿瘤（KOT）与上皮细胞之间以及 KOT 与角化蛋白之间存在关联。细胞块切片中胆固醇结晶裂隙的出现与囊性病变相关，而角化蛋白的存在是 KOT 的一个指标。细胞块技术快速、易于操作且成本低廉，是一种有吸引力的颌骨病变初步诊断的辅助方法。
