Robinson Robert A
Department of Pathology, University of Iowa, Iowa City, IA, USA.
Mod Pathol. 2017 Jan;30(s1):S96-S103. doi: 10.1038/modpathol.2016.191.
Odontogenic cysts and osseous lesions are often seen as challenging diagnostic lesions but the majority of them are easily classified. This article outlines the diagnostic features required for separating the most common of odontogenic cysts and select osseous lesions of the jaws. Clinical and radiographic findings of these jaw lesions often lead to a differential diagnosis that only the histologic findings will clarify. Dentigerous cyst, keratocystic odontogenic tumor, and certain ameloblastomas that have cystic change, may have identical radiographic findings, with only separation by their specific histologic features leading to the significantly different treatments required for each. Conversely, some cystic lesions can appear histologically identical and cannot be diagnosed without the radiographic findings. Certain osseous lesions of the jaws are particularly problematic for diagnosis without the appropriate radiographic findings, and the diagnosis should probably not be attempted on the histologic findings alone. This article will integrate the necessary clinical, radiographic, and histologic findings required to address the most common odontogenic lesions.
牙源性囊肿和骨病变通常被视为具有挑战性的诊断病变，但其中大多数很容易分类。本文概述了区分最常见牙源性囊肿和特定颌骨骨病变所需的诊断特征。这些颌骨病变的临床和影像学表现常常导致鉴别诊断，而只有组织学检查结果才能明确诊断。含牙囊肿、牙源性角化囊性瘤以及某些发生囊性改变的成釉细胞瘤，可能具有相同的影像学表现，只有通过其特定的组织学特征才能区分，而这会导致对每种病变采取截然不同的治疗方法。相反，一些囊性病变在组织学上可能表现相同，没有影像学表现则无法诊断。某些颌骨骨病变在没有适当影像学表现时诊断特别困难，仅依靠组织学表现可能无法做出诊断。本文将整合诊断最常见牙源性病变所需的必要临床、影像学和组织学表现。
