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丙型肝炎病毒预防、护理和治疗:从政策到实践。

Hepatitis C virus prevention, care, and treatment: from policy to practice.

机构信息

Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA.

出版信息

Clin Infect Dis. 2012 Jul;55 Suppl 1:S58-63. doi: 10.1093/cid/cis392.

DOI:10.1093/cid/cis392
PMID:22715216
Abstract

The prevention of hepatitis C virus (HCV) infection and associated health conditions (eg, cirrhosis and hepatocellular carcinoma) is a public health priority in the United States. Hepatitis C virus-related morbidity and mortality is increasing at a time when the advent of highly effective therapies greatly increases opportunities to prevent HCV transmission and disease. In 2010, the Institute of Medicine recommended that national action be taken to address this "underappreciated health concern for the nation." In response, in 2011, the US Department of Health and Human Services (HHS) published a viral hepatitis action plan that guides response to the viral hepatitis epidemic by providing explicit steps to be undertaken by specific HHS agencies to improve provider training and community education; expand access to testing, care, and treatment; strengthen public health surveillance; improve HCV preventive services for injection drug users; develop a hepatitis C vaccine; and prevent HCV transmission in healthcare settings. For all aspects of the action plan, infectious disease specialists and other clinicians assume a key role in efforts to reduce HCV-related morbidity and mortality. With successful collaboration of the public and private sectors, the hepatitis C epidemic can be forever silenced.

摘要

预防丙型肝炎病毒 (HCV) 感染和相关健康状况(例如肝硬化和肝细胞癌)是美国的一项公共卫生重点。当高效疗法的出现大大增加了预防 HCV 传播和疾病的机会时,丙型肝炎病毒相关发病率和死亡率正在上升。2010 年,美国医学研究所建议采取国家行动来解决这一“被低估的全国健康问题”。作为回应,2011 年,美国卫生与公众服务部 (HHS) 发布了一份病毒性肝炎行动计划,通过为特定 HHS 机构提供明确的步骤来指导对病毒性肝炎流行的应对,以改善提供者培训和社区教育;扩大检测、护理和治疗的机会;加强公共卫生监测;改善注射吸毒者的 HCV 预防服务;开发丙型肝炎疫苗;并防止医疗保健环境中的 HCV 传播。在行动计划的所有方面,传染病专家和其他临床医生在减少 HCV 相关发病率和死亡率方面都发挥着关键作用。通过公私部门的成功合作,可以永远消除丙型肝炎流行。

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