真核起始因子2的纯化制剂逆转干扰素诱导的蛋白质合成阻断 - Suppr | 超能文献

Reversal of the interferon-induced block of protein synthesis by purified preparations of eucaryotic initiation factor 2.

作者信息

Kaempfer R, Israeli R, Rosen H, Knoller S, Zilberstein A, Schmidt A, Revel M

出版信息

Virology. 1979 Nov;99(1):170-3. doi: 10.1016/0042-6822(79)90049-7.

DOI:10.1016/0042-6822(79)90049-7

Abstract

摘要

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Reversal of the interferon-induced block of protein synthesis by purified preparations of eucaryotic initiation factor 2.真核起始因子2的纯化制剂逆转干扰素诱导的蛋白质合成阻断

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The inhibition of translation of synthetic polyribonucleotides and mengo RNA in extracts from interferon-treated L cells and its reversion by yeast tRNAs.干扰素处理的L细胞提取物中合成多聚核糖核苷酸和门戈病毒RNA翻译的抑制作用及其被酵母tRNA逆转的情况。

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Mengovirus-induced inhibition of cell protein synthesis and subsequent recovery of cellular activity in interferon-pretreated cells.脑心肌炎病毒诱导的干扰素预处理细胞中细胞蛋白质合成的抑制及随后细胞活性的恢复。

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Mechanism of the interferon-induced block of mRNA translation in mouse L cells: reversal of the block by transfer RNA.干扰素诱导小鼠L细胞中mRNA翻译受阻的机制：转运RNA对该阻断作用的逆转

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Molecular mechanisms of interferon action: interferon-mediated phosphorylation of ribosome-associated protein P1 and protein synthesis initiation factor eIF-2.干扰素作用的分子机制：干扰素介导的核糖体相关蛋白P1和蛋白质合成起始因子eIF-2的磷酸化

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Dual action of double-stranded RNA inhibiting protein synthesis in extracts of interferon-treated mouse L cells. Translation is impaired at the level of initiation and by mRNA degradation.双链RNA在经干扰素处理的小鼠L细胞提取物中抑制蛋白质合成的双重作用。翻译在起始水平受到损害，并通过信使核糖核酸降解。

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Control of protein synthesis in extracts from poliovirus-infected cells. I. mRNA discrimination by crude initiation factors.脊髓灰质炎病毒感染细胞提取物中蛋白质合成的控制。I. 粗起始因子对mRNA的识别

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Specific binding of eukaryotic initiation factor 2 to satellite tobacco necrosis virus RNA at a 5'-terminal sequence comprising the ribosome binding site.真核起始因子2与烟草卫星坏死病毒RNA在包含核糖体结合位点的5'-末端序列处的特异性结合。

Proc Natl Acad Sci U S A. 1981 Mar;78(3):1542-6. doi: 10.1073/pnas.78.3.1542.

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Regulation of the antiviral and anticellular activities of interferon by exogenous double-stranded RNA.外源性双链RNA对干扰素抗病毒和抗细胞活性的调节

Mol Cell Biochem. 1983;52(2):153-60. doi: 10.1007/BF00224924.

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The interferon renaissance: molecular aspects of induction and action.干扰素的复兴：诱导与作用的分子层面

Microbiol Rev. 1981 Jun;45(2):244-66. doi: 10.1128/mr.45.2.244-266.1981.