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[三种退行性疾病(肌萎缩侧索硬化症、少桥脑小脑萎缩和进行性核上性麻痹)夜间睡眠的多导睡眠图研究]

[Polygraphic study of nocturnal sleep in three degenerative diseases: ALS, oligo-ponto-cerebellar atrophy, and progressive supranuclear palsy].

作者信息

Laffont F, Autret A, Minz M, Beillevaire T, Gilbert A, Cathala H P

出版信息

Waking Sleeping. 1979 Jan;3(1):17-30.

PMID:227177
Abstract

A polygraphic study of nocturnal sleep was carried out on 12 patients suffering from amyotrophic lateral sclerosis (ALS), 6 patients suffering from olivio-ponto-cerebellare-atrophia (OPCA) and 9 patients suffering from the Steele-Richardson disease (SR). A disturbance of sleep--if it exists--always runs parallel with the course of the disease. No disturbances were registered in the group of patients suffering from ALS, in the OPCA group a specific disease of paradoxal sleep is observed. The sleep disturbances are more global in the group of patients suffering from the SR disease. A particular electrooculogram was taken from the patients from the awakening and from the paradoxal sleep. Respiratory difficulties were registered on certain patients of each of the three groups. These sleep disturbances, registered by the polygraph, were compared with those observed on patients presenting a cortical disease.

摘要

对12例肌萎缩侧索硬化症(ALS)患者、6例橄榄脑桥小脑萎缩(OPCA)患者和9例斯蒂尔-理查森病(SR)患者进行了夜间睡眠的多导睡眠图研究。睡眠障碍——如果存在的话——总是与疾病进程平行。ALS患者组未记录到睡眠障碍,OPCA组观察到一种特殊的快速眼动睡眠疾病。SR病患者组的睡眠障碍更为普遍。从觉醒和快速眼动睡眠的患者身上获取了特定的眼电图。三组中的某些患者都记录到了呼吸困难。将多导睡眠图记录的这些睡眠障碍与患有皮质疾病的患者所观察到的睡眠障碍进行了比较。

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