Massetani R, Arena R, Bonuccelli U, Salerno P, Muratorio A
Riv Patol Nerv Ment. 1982 Sep-Oct;103(5):215-24.
Nocturnal sleep was poligraphycally recorded in three male patients aged 54-67, with progressive supranuclear palsy (PSP). All patients suffered from insomnia. In case 1 REM sleep was markedly reduced and spindles were less numerous than in normal subjects. In cases 2 and 3, EEG patterns were not distinguishable from those observed when the patients were awake. Sleep, therefore, was recognized only by constant observation of the patients. As seen in the literature EEG changes during sleep can be correlated to the severity of the clinical picture and the stage of evolution of the disease. EEG patterns of sleep in PSP are similar to those reported in patients with presenile dementia.
对三名年龄在54至67岁之间、患有进行性核上性麻痹(PSP)的男性患者进行了多导睡眠图夜间睡眠记录。所有患者均患有失眠症。病例1的快速眼动睡眠明显减少,且纺锤波数量少于正常受试者。病例2和病例3中,脑电图模式与患者清醒时观察到的模式无法区分。因此,只有通过持续观察患者才能识别睡眠状态。如文献中所见,睡眠期间的脑电图变化可与临床表现的严重程度和疾病进展阶段相关联。PSP患者的睡眠脑电图模式与早老性痴呆患者报告的模式相似。