Antibody targeted therapy in cancer: comparison of murine and clinical studies.
作者信息
Begent R H, Pedley R B
机构信息
Cancer Research Campaign Laboratories, Charing Cross and Westminster Medical School, London, U.K.
出版信息
Cancer Treat Rev. 1990 Sep;17(2-3):373-8. doi: 10.1016/0305-7372(90)90071-m.
PMID:2272053
Abstract
Antibody targeted therapy can be effective in animal models of cancer. Treatment has been less successful in man, though some responses are reported. Understanding the distribution of antibody in man and animals shows how toxicity may be minimized and patients selected for therapy on the basis of efficient antibody localization in the tumour.
摘要
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