Kukanich Butch
Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, 228 Coles Hall, Manhattan, KS 66506, USA.
Vet Clin North Am Small Anim Pract. 2012 Jul;42(4):631-42, v. doi: 10.1016/j.cvsm.2012.04.007. Epub 2012 May 10.
Geriatric dogs and cats are an important group of patients in veterinary medicine. Healthy geriatric patients have similar physiology and presumably pharmacology as healthy adult animals. Geriatric patients with subclinical organ dysfunction are overtly healthy but have some organ dysfunction that may alter the clinical pharmacology of some drugs. Geriatric patients with an overt disease are expected to have altered drug pharmacology for some drugs based on the underlying disease. Diseases including cardiovascular, renal, hepatic, osteoarthritis, neurologic, and neoplastic are expected in the geriatric population and discussed, including the effects of the underlying disease and potential drug-drug interactions.
老年犬猫是兽医医学中一类重要的病患群体。健康的老年病患与健康成年动物具有相似的生理学特征，药理学特征可能也相似。患有亚临床器官功能障碍的老年病患表面上健康，但存在一些可能改变某些药物临床药理学特性的器官功能障碍。患有显性疾病的老年病患，基于潜在疾病，预计某些药物的药理学特性会发生改变。老年群体易患包括心血管、肾脏、肝脏、骨关节炎、神经和肿瘤等疾病，并对此进行了讨论，包括潜在疾病的影响以及潜在的药物相互作用。
