Liu E T
Department of Medicine, University of North Carolina, Chapel Hill.
Clin Lab Med. 1990 Dec;10(4):797-807.
Mutations in the ras genes frequently are found in myeloproliferative disorders. These abnormalities have prognostic significance in the myelodysplastic syndromes, but their clinical importance in other hematopathic states remains unclear. The study of this gene in leukemic conditions is providing insights into the genetic pathways leading to leukemic progression.
ras基因的突变在骨髓增殖性疾病中经常被发现。这些异常在骨髓增生异常综合征中具有预后意义，但它们在其他血液病状态中的临床重要性仍不清楚。在白血病情况下对该基因的研究正在为导致白血病进展的遗传途径提供见解。
