Department of Otolaryngology, Head and Neck Surgery, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
Department of Otolaryngology, Harvard Medical School and Eaton-Peabody Laboratories, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, USA.
Ear Hear. 2020 May/Jun;41(3):500-507. doi: 10.1097/AUD.0000000000000787.
The main objective of this study is to determine whether chronic sound deprivation leads to poorer speech discrimination in humans.
We reviewed the audiologic profile of 240 patients presenting normal and symmetrical bone conduction thresholds bilaterally, associated with either an acute or chronic unilateral conductive hearing loss of different etiologies.
Patients with chronic conductive impairment and a moderate, to moderately severe, hearing loss had lower speech recognition scores on the side of the pathology when compared with the healthy side. The degree of impairment was significantly correlated with the speech recognition performance, particularly in patients with a congenital malformation. Speech recognition scores were not significantly altered when the conductive impairment was acute or mild.
This retrospective study shows that chronic conductive hearing loss was associated with speech intelligibility deficits in patients with normal bone conduction thresholds. These results are as predicted by a recent animal study showing that prolonged, adult-onset conductive hearing loss causes cochlear synaptopathy.
本研究的主要目的是确定慢性声音剥夺是否会导致人类言语辨别力下降。
我们回顾了 240 名患者的听力学特征，这些患者双侧的骨导阈值正常且对称，伴有单侧急性或慢性传导性听力损失，病因不同。
与健侧相比，患有慢性传导性听力损失和中等到中重度听力损失的患者在病变侧的言语识别得分较低。听力损失程度与言语识别能力显著相关，尤其是在患有先天性畸形的患者中。当传导性听力损失为急性或轻度时，言语识别得分没有明显改变。
这项回顾性研究表明，慢性传导性听力损失与正常骨导阈值患者的言语清晰度缺陷有关。这些结果与最近的一项动物研究结果一致，该研究表明，成人发病的长期传导性听力损失会导致耳蜗突触病。
