Department of Otolaryngology Head and Neck Surgery, Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Israel.
Otol Neurotol. 2012 Aug;33(6):996-7. doi: 10.1097/MAO.0b013e31825e73e0.
To investigate a possible contribution of handedness to the development of unilateral acquired cholesteatoma.
All patients with unilateral acquired cholesteatoma attending otorhinolaryngology clinic between August 2009 and February 2012 were asked about their handedness.
The study group consisted of 237 right-handed and 31 left-handed (11.8%) patients who included 158 male (59%) and 79 female subjects with an age range of 6 to 81 years (mean, 38.6 yr). There were no ambidexters in the present cohort. Overall, unilateral cholesteatoma involved 146 right (54.5%) and 122 left ears (45.5%). Ten of 31 patients (32.3%) with left hand predominance were female subjects. In the unilateral disease, the right ears were affected more frequently in patients with right-hand dominance (59.5%), and the left ears were more frequently affected in the left-handed patients (83.9%); this difference was statistically significant (p < 0.0001). The sex differences in the distribution of cholesteatoma side and handedness were not statistically significant (p = 0.098).
The strong relationship has been observed between the patient's handedness, and laterality of the unilateral acquired cholesteatoma may have contribution in the multifactorial process of cholesteatoma formation.
研究利手是否可能对单侧后天性胆脂瘤的发生有影响。
2009 年 8 月至 2012 年 2 月期间在耳鼻喉科诊所就诊的所有单侧后天性胆脂瘤患者均被询问其利手习惯。
研究组包括 237 名惯用右手者和 31 名惯用左手者（11.8%），其中 158 名男性（59%）和 79 名女性，年龄 6 至 81 岁（平均 38.6 岁）。本队列中没有双手惯用者。总的来说，单侧胆脂瘤累及 146 例右侧（54.5%）和 122 例左侧耳朵（45.5%）。10 名（32.3%）左手优势患者为女性。在单侧疾病中，右利手患者的右耳更常受累（59.5%），左利手患者的左耳更常受累（83.9%）；这种差异具有统计学意义（p < 0.0001）。胆脂瘤侧和利手分布的性别差异无统计学意义（p = 0.098）。
患者的利手与单侧后天性胆脂瘤的侧别之间存在强烈的相关性，胆脂瘤形成的多因素过程中可能存在利手的影响。
