惯用手和帕金森病症状的优势侧。
Handedness and dominant side of symptoms in Parkinson's disease.
机构信息
Department of Neurology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
出版信息
Parkinsonism Relat Disord. 2011 Jan;17(1):58-60. doi: 10.1016/j.parkreldis.2010.10.002. Epub 2010 Oct 25.
The aim of this retrospective study was to assess the presence of a possible association between handedness and the side of symptom dominance in 963 patients with Parkinson's disease (PD). In only 287 patients the hand dominance was registered. Out of 254 right-handed patients, 158 (62%) had a right-side dominance of PD symptoms, while 96 patients (38%) had left-lateralized symptom dominance (p < 0.001). For the 33 left-handed subjects, 18 (55%) had left- and 15 (45%) had right-sided symptom dominance (p = 0.602). Right-handedness thus appeared to be associated with right-sided dominance of PD symptoms, while the group of left-handed patients was too small to draw conclusions from. Possible explanations are discussed.
本回顾性研究旨在评估 963 例帕金森病（PD）患者中利手与症状优势侧之间可能存在的关联。在仅 287 例患者中记录了手的优势性。在 254 名右利手患者中，158 名（62%）PD 症状有右侧优势，而 96 名患者（38%）有左侧症状优势（p<0.001）。对于 33 名左利手患者，18 名（55%）有左侧症状优势，15 名（45%）有右侧症状优势（p=0.602）。因此，右利手似乎与 PD 症状的右侧优势有关，而左利手患者的人数太少，无法得出结论。讨论了可能的解释。
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