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食物过敏:从诊断到治疗。

Food allergy: from diagnosis to treatment.

机构信息

T.A.R.G.I.D., Gasthuisberg University Hospitals, Catholic University of Leuven, Belgium.

出版信息

Dig Dis. 2012;30(2):224-31. doi: 10.1159/000336709. Epub 2012 Jun 20.

Abstract

Adverse food reactions, an adverse health effect arising from an immune or nonimmune response that occurs reproducibly on the exposure to a given food, can be divided into toxic and hypersensitivity reactions. When an immunologic mechanism has been shown, hypersensitivity food reactions should be referred to as food allergy that may be IgE- or non-IgE-mediated. Food allergy diagnosis is mainly guided by a correct and accurate history and physical examination, thus leading to prick test and elimination diets. The treatment gold standard is still represented by an elimination diet together with antihistamines and corticosteroid usage in order to reduce the gastrointestinal and potentially life-threatening systemic symptoms. Other treatments are currently under investigation with promising results.

摘要

食物不良反应是一种由免疫或非免疫反应引起的不良健康影响,在重复接触某种食物时会发生,可分为毒性反应和过敏反应。当免疫机制已被证明时,过敏反应性食物反应应被称为食物过敏,可能是 IgE 介导或非 IgE 介导的。食物过敏的诊断主要由正确和准确的病史和体格检查指导,从而导致皮试和排除饮食。治疗的金标准仍然是排除饮食加上抗组胺药和皮质类固醇的使用,以减少胃肠道和潜在危及生命的全身症状。其他治疗方法目前正在研究中,结果有很大希望。

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