• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation.

作者信息

Yang C S, Yoo J S, Ishizaki H, Hong J Y

机构信息

Department of Chemical Biology and Pharmacognosy College of Pharmacy, Rutgers University, Piscataway, New Jersey 08855-0789.

出版信息

Drug Metab Rev. 1990;22(2-3):147-59. doi: 10.3109/03602539009041082.

DOI:10.3109/03602539009041082
PMID:2272285
Abstract
摘要

相似文献

1
Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation.细胞色素P450IIE1：在亚硝胺代谢中的作用及调控机制
Drug Metab Rev. 1990;22(2-3):147-59. doi: 10.3109/03602539009041082.
2
Cytochrome P4502E1 genetic polymorphisms and risk of nasopharyngeal carcinoma: results from a case-control study conducted in Taiwan.细胞色素P4502E1基因多态性与鼻咽癌风险：在台湾进行的一项病例对照研究结果
Cancer Epidemiol Biomarkers Prev. 1995 Sep;4(6):607-10.
3
Pyridine effects on expression and molecular regulation of the cytochrome P450IA gene subfamily.吡啶对细胞色素P450IA基因亚家族表达及分子调控的影响。
Mol Pharmacol. 1991 Jul;40(1):52-7.
4
Metabolism of nitrosamines by cytochrome P-450 isozymes.细胞色素P-450同工酶对亚硝胺的代谢
IARC Sci Publ. 1984(57):423-8.
5
Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.微粒体乙醇氧化系统：细胞色素P450，CYP2E1的转录和转录后调控
Alcohol Alcohol Suppl. 1991;1:97-101.
6
High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks.香烟烟雾对小鼠肾脏CYP2E1基因的高诱导性及其对DNA单链断裂的可能影响。
Biochem Biophys Res Commun. 1996 Feb 15;219(2):429-34. doi: 10.1006/bbrc.1996.0250.
7
Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazone: a putative measure of CYP2E1 activity.
Pharmacogenetics. 1994 Jun;4(3):162-5.
8
Stable expression of human cytochrome P450IIE1 in mammalian cells: metabolic activation of nitrosodimethylamine and formation of adducts with cellular DNA.人细胞色素P450IIE1在哺乳动物细胞中的稳定表达：二甲基亚硝胺的代谢激活及与细胞DNA加合物的形成
Cancer Res. 1992 Apr 1;52(7):1796-800.
9
Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs.豚鼠体内抗坏血酸对CYP1A和CYP3A信使核糖核酸的调控
Arch Biochem Biophys. 1997 Dec 15;348(2):268-77. doi: 10.1006/abbi.1997.0409.
10
Molecular basis for the sex-related difference in renal N-nitrosodimethylamine demethylase in C3H/HeJ mice.C3H/HeJ小鼠肾N-亚硝基二甲胺脱甲基酶性别相关差异的分子基础。
Cancer Res. 1989 Jun 1;49(11):2973-9.

引用本文的文献

1
Nitrosamines crisis in pharmaceuticals - Insights on toxicological implications, root causes and risk assessment: A systematic review.药品中的亚硝胺危机——关于毒理学影响、根本原因和风险评估的见解：一项系统综述
J Pharm Anal. 2024 May;14(5):100919. doi: 10.1016/j.jpha.2023.12.009. Epub 2023 Dec 12.
2
Metabolic Activation and DNA Interactions of Carcinogenic -Nitrosamines to Which Humans Are Commonly Exposed.致癌亚硝胺在人类中常见的代谢激活与 DNA 相互作用。
Int J Mol Sci. 2022 Apr 20;23(9):4559. doi: 10.3390/ijms23094559.
3
The effect of Crocin on sperm parameters disorders induced by peripheral administration of nitrosamines in male rats.
西红花酸对硝胺类药物经外周给药诱导雄性大鼠精子参数紊乱的影响。
J Med Life. 2022 Mar;15(3):362-367. doi: 10.25122/jml-2019-0144.
4
Gut Microbiota-Derived Metabolites in Colorectal Cancer: The Bad and the Challenges.结直肠癌中肠道微生物群衍生的代谢产物：有害之处与挑战
Front Oncol. 2021 Oct 18;11:739648. doi: 10.3389/fonc.2021.739648. eCollection 2021.
5
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice.Sirt1 缺乏会上调谷胱甘肽代谢，从而预防小鼠肝癌的发生。
Oncogene. 2021 Oct;40(41):6023-6033. doi: 10.1038/s41388-021-01993-1. Epub 2021 Aug 25.
6
The protective effect of Pentoxifylline on testopathy in male rats following Dimethyl Nitrosamine administration: An experimental study.己酮可可碱对雄性大鼠给予二甲基亚硝胺后睾丸病变的保护作用：一项实验研究。
Int J Reprod Biomed. 2019 Nov 7;17(10):727-738. doi: 10.18502/ijrm.v17i10.5292. eCollection 2019 Oct.
7
Alcoholic Liver Disease: Alcohol Metabolism, Cascade of Molecular Mechanisms, Cellular Targets, and Clinical Aspects.酒精性肝病：酒精代谢、分子机制级联、细胞靶点及临床方面
Biomedicines. 2018 Nov 12;6(4):106. doi: 10.3390/biomedicines6040106.
8
Mechanistic Evidence for Red Meat and Processed Meat Intake and Cancer Risk: A Follow-up on the International Agency for Research on Cancer Evaluation of 2015.红肉和加工肉类摄入与癌症风险的机制证据：对国际癌症研究机构2015年评估的随访
Chimia (Aarau). 2018 Oct 31;72(10):718-724. doi: 10.2533/chimia.2018.718.
9
Tramadol-induced hepato- and nephrotoxicity in rats: Role of Curcumin and Gallic acid as antioxidants.曲马多诱导的大鼠肝毒性和肾毒性：姜黄素和没食子酸作为抗氧化剂的作用。
PLoS One. 2018 Aug 15;13(8):e0202110. doi: 10.1371/journal.pone.0202110. eCollection 2018.
10
Thyroid and reproductive hormones disruption as well as kallikrein-3 level in dimethyl nitrosamine-induced toxicity: Effects of ascorbate treatment in male wistar rats.甲状腺和生殖激素紊乱以及二甲基亚硝胺诱导毒性中的激肽释放酶-3水平：抗坏血酸处理对雄性Wistar大鼠的影响。
Biochim Open. 2016 Sep 28;3:40-46. doi: 10.1016/j.biopen.2016.09.002. eCollection 2016 Dec.