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免疫细胞化学技术在确定前脑脑室下区与纹状体边界中的应用

[Application of immunocytochemical technique for the determination of the border between forebrain subventricular zone and striatum].

作者信息

Kirik O V, Grigor'ev I P, Sukhorukova E G, Pavlova N V, Korzhevskiĭ D E

出版信息

Morfologiia. 2012;141(1):81-4.

Abstract

Forebrain subventricular zone (SVZ)--the putative major source of neural stem cells in the brain of adult mammals--can hardly be visualized using routine histological staining. The present study was focused on the possibility of application of immunocytochemical approach for accurate delineation of the border between SVZ and striatum. It was shown that immunocytochemical reactions demonstrating tyrosine hydroxylase or synaptophysin were optimal for the determination of the border between SVZ and striatum in different mammals.

摘要

前脑脑室下区(SVZ)——成年哺乳动物大脑中神经干细胞的假定主要来源——使用常规组织学染色很难可视化。本研究聚焦于应用免疫细胞化学方法精确描绘SVZ与纹状体之间边界的可能性。结果表明,显示酪氨酸羟化酶或突触素的免疫细胞化学反应最适合确定不同哺乳动物中SVZ与纹状体之间的边界。

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