Cazzullo C L, Gala C, Ducati A, Landi A, Donati R, Russo R, Rossini M, Nicolosi A
Istituto di Clinica Psichiatrica, Università degli Studi di Milano.
Ital J Neurol Sci. 1990 Oct;11(5):481-5. doi: 10.1007/BF02336568.
18 subjects with symptomless HIV infection were investigated with multimodal evoked potentials for possible CNS involvement and again after an 8-12 month interval. 13 subjects showed neuropsychological changes, which were confirmed at the second examination. The 5 subjects found normal remained so at the second examination. On WAIS assessment the only patient to earn pathological scores was the one with the greatest evoked potentials changes. Thus the evoked potentials procedure proved capable of identifying early CNS involvement by HIV infection.
对18例无症状HIV感染者进行了多模式诱发电位检查，以确定是否可能存在中枢神经系统受累，并在间隔8 - 12个月后再次进行检查。13例受试者出现神经心理学变化，在第二次检查时得到证实。另外5例首次检查正常的受试者在第二次检查时仍保持正常。在韦氏成人智力量表（WAIS）评估中，诱发电位变化最大的患者是唯一获得病理评分的患者。因此，诱发电位检查方法被证明能够识别HIV感染早期的中枢神经系统受累情况。
