El Rhaffouli H, El Boukhrissi F, Bajjou T, Laraqui A, Hilali F, Bahji M, El Harrak M, Lahlou Amine I
Laboratoire de recherche et de biosécurité, faculté de médecine et de pharmacie, université Mohammed V-Souissi, hôpital Militaire d'instruction Mohammed V, Hay Ryad, Rabat, Maroc.
Pathol Biol (Paris). 2013 Apr;61(2):83-6. doi: 10.1016/j.patbio.2012.05.004. Epub 2012 Jun 22.
To study and to compare the prevalence of infection with the virus A(H1N1)pdm 2009 in the population of two regions of Morocco compared to preexisting antibody levels.
A total of 300 and 200 serum samples were collected in the region of Rabat and Meknes respectively. Samples were collected during March to April 2011. One hundred and fifty sera, collected in 2007 from blood donors, were recovered from the blood center. The research for antibodies to influenza A(H1N1)pdm09 was performed by hemagglutination inhibition assay.
The overall prevalence of antibodies inhibiting hemagglutination at the Rabat region (67%) is significantly higher than that of Meknes (53%) while the rate of cross-reactive antibodies was 7.3%. The subjects under 25 years from the Rabat region have infection rates as high with an odds ratio of 2.45. Individuals with comorbidities have the lowest prevalence with an odds ratio of 0.61. The rate of influenza A(H1N1)pdm09 vaccination in the Rabat region is 7%.
Immunization rates of the Moroccan population will prevent the occurrence of large outbreaks in the year 2011 to 2012 but the persistence of a naive population justifies the continuation of vaccination against A(H1N1)pdm09.
研究并比较2009年甲型H1N1流感病毒在摩洛哥两个地区人群中的感染率，并与既往抗体水平作比较。
分别在拉巴特和梅克内斯地区共采集了300份和200份血清样本。样本采集于2011年3月至4月期间。从血液中心找回了2007年从献血者处采集的150份血清。通过血凝抑制试验检测甲型H1N1流感病毒抗体。
拉巴特地区血凝抑制抗体的总体流行率（67%）显著高于梅克内斯地区（53%），而交叉反应抗体率为7.3%。拉巴特地区25岁以下人群的感染率同样很高，优势比为2.45。患有合并症的个体患病率最低，优势比为0.61。拉巴特地区甲型H1N1流感病毒疫苗接种率为7%。
摩洛哥人群的免疫接种率将预防2011年至2012年大规模疫情的发生，但仍有未免疫人群存在，因此有必要继续接种甲型H1N1流感病毒疫苗。
