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子痫前期与心血管风险。

Preeclampsia and cardiovascular risk.

作者信息

Hermes W, Van Kesteren F, De Groot C J M

机构信息

Department of Obstetrics and Gynecology, Medical Center Haaglanden and Vu University Medical CenterThe Hague, the Netherlands.

出版信息

Minerva Ginecol. 2012 Aug;64(4):281-92.

Abstract

The association between preeclampsia and cardiovascular disease has been an increasing area of interest over the last years. Cardiovascular disease is the number one cause of death in women in the western world and more women than men die of heart disease each year. The most common pregnancy disorder is preeclampsia. Preeclampsia is defined by hypertension and de novo proteinuria and remains responsible for high maternal and fetal morbidity and mortality worldwide. Pregnancy has been described as a "stress test" for future cardiovascular disease, to identify women young enough to benefit from screening. Women with a history of early onset (severe) preeclampsia have the highest risk of cardiovascular disease later. However, the exact underlying link between the two disorders is still unknown. In this review we describe different facets of the association between preeclampsia and cardiovascular disease and we give an overview of the recent literature.

摘要

近年来,子痫前期与心血管疾病之间的关联一直是一个越来越受关注的领域。在西方世界,心血管疾病是女性的首要死因,每年死于心脏病的女性比男性多。最常见的妊娠疾病是子痫前期。子痫前期的定义为高血压和新发蛋白尿,在全球范围内,它仍是导致孕产妇和胎儿高发病率和死亡率的原因。妊娠被描述为对未来心血管疾病的“压力测试”,以识别年龄足够小、能从筛查中受益的女性。有早发型(重度)子痫前期病史的女性日后患心血管疾病的风险最高。然而,这两种疾病之间确切的潜在联系仍然未知。在这篇综述中,我们描述了子痫前期与心血管疾病关联的不同方面,并对近期文献进行了概述。

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