Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.
Chem Commun (Camb). 2012 Aug 4;48(60):7444-6. doi: 10.1039/c2cc33356b. Epub 2012 Jun 22.
A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2'-deoxy and 2',3'-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction.
一种独特的光化学反应流动反应器,具有石英管、铝镜和温度控制,已被开发用于光诱导电子转移脱氧反应,以产生 2'-脱氧和 2',3'-二脱氧核苷。连续流动形式显著提高了反应的效率和选择性。