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一种爬行动物发育中和成年脊髓中的神经肽Y（NPY）及其C端侧翼肽（C-PON）

Neuropeptide tyrosine (NPY) and its C-terminal flanking peptide (C-PON) in the developing and adult spinal cord of a reptile.

作者信息

Marti E, Bello A R, Lancha A, Batista M A

机构信息

U.D.I. Biología Celular, Facultad de Biología, Universidad de La Laguna, Tenerife, Spain.

出版信息

J Anat. 1990 Oct;172:149-56.

PMID:2272899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1257210/
Abstract

The developmental pattern and the adult distribution of neuropeptide tyrosine (NPY) and its C-terminal flanking peptide (C-PON) were investigated in the spinal cord of the lizard Gallotia galloti. Embryonic, postnatal and adult animals were studied by means of the immunohistochemical technique. Neurons containing both peptide immunoreactivities first appeared at the embryonic Stages 37/38. Immunoreactive perikarya were more numerous in the embryonic than in either the postnatal or the adult spinal cord. Fibres immunoreactive for both antisera appeared around the time of hatching, being numerous and widespread in the adult spinal cord. NPY- and C-PON-like-containing neurons and fibres in the adult spinal cord of Gallotia galloti were related to sensory, autonomic and motor areas.

摘要

研究了加那利岛蜥蜴（Gallotia galloti）脊髓中神经肽Y（NPY）及其C端侧翼肽（C-PON）的发育模式和成年分布。采用免疫组织化学技术对胚胎期、出生后及成年动物进行了研究。同时含有两种肽免疫反应性的神经元最早出现在胚胎第37/38阶段。胚胎期脊髓中免疫反应性核周体的数量比出生后或成年脊髓中的更多。两种抗血清的免疫反应性纤维在孵化时出现，在成年脊髓中数量众多且分布广泛。加那利岛蜥蜴成年脊髓中含NPY样和C-PON样的神经元及纤维与感觉、自主神经和运动区域有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/1f3d3ecdd558/janat00038-0152-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/c46f18126268/janat00038-0152-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/a6f9d6c62de0/janat00038-0152-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/5f1f3376d900/janat00038-0152-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/2dbde27e5308/janat00038-0152-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/09ace0d4354a/janat00038-0152-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/1f3d3ecdd558/janat00038-0152-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/c46f18126268/janat00038-0152-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/a6f9d6c62de0/janat00038-0152-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/5f1f3376d900/janat00038-0152-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/2dbde27e5308/janat00038-0152-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/09ace0d4354a/janat00038-0152-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e91/1257210/1f3d3ecdd558/janat00038-0152-f.jpg

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本文引用的文献

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Prenatal ontogeny of neurons with enkephalin-like immunoreactivity in the rat central nervous system: an immunohistochemical mapping investigation.大鼠中枢神经系统中具有脑啡肽样免疫反应性的神经元的产前个体发生：一项免疫组织化学定位研究。
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Ontogeny of the peptidergic system in the rat spinal cord: immunohistochemical analysis.大鼠脊髓肽能系统的个体发生：免疫组织化学分析
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Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.大鼠中枢神经系统中神经肽Y（NPY）样免疫反应性与儿茶酚胺的差异共存
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Localization and identification of neuropeptide Y (NPY)-like immunoreactivity in the frog brain.蛙脑内神经肽Y（NPY）样免疫反应性的定位与鉴定
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