Bhunia A K, Johnson M C, Ray B, Belden E L
Department of Animal Science, University of Wyoming, Laramie 82071.
J Appl Bacteriol. 1990 Aug;69(2):211-5. doi: 10.1111/j.1365-2672.1990.tb01511.x.
Pediocin AcH, a bacteriocin of Pediococcus acidilactici H, inhibits the growth of several food spoilage and pathogenic bacteria. The antigenic property of partially purified pediocin AcH was tested by immunizing mice and a rabbit. Pediocin AcH was not immunogenic in these animals as determined by immunoblotting even after conjugation to bovine serum albumin. The non-immunogenic nature of pediocin AcH, its non-toxicity to laboratory animals and its hydrolysis by gastric proteolytic enzymes may be considered favourably in its possible use as a food preservative.
嗜酸乳杆菌H的细菌素Pediocin AcH可抑制多种食品腐败菌和病原菌的生长。通过对小鼠和兔子进行免疫来测试部分纯化的Pediocin AcH的抗原特性。经免疫印迹法测定，即使与牛血清白蛋白结合后，Pediocin AcH在这些动物中也无免疫原性。Pediocin AcH的非免疫原性、对实验动物的无毒以及被胃蛋白水解酶水解的特性，在其作为食品防腐剂的潜在应用中可能是有利的。
