谱域眼前节光学相干断层扫描在微生物角膜炎中的应用。
Spectral domain anterior segment optical coherence tomography in microbial keratitis.
机构信息
Ophthalmology Department, Assiut University Hospitals, Assiut University, Assiut, Egypt.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2013 Feb;251(2):549-53. doi: 10.1007/s00417-012-2086-5. Epub 2012 Jun 24.
PURPOSE
To investigate the spectral domain anterior segment optical coherence tomography (SDAS-OCT) patterns in microbial keratitis (fungal and bacterial keratitis).
DESIGN
Prospective, cross-sectional, observational study.
METHODS
Twenty eyes of 20 patients with proven fungal and bacterial microbial keratitis, at different stages of the disease, underwent SDAS-OCT imaging.
RESULTS
Eight eyes presented with proven bacterial keratitis (3 Staphylococcus Aureus, 2 Pseudomonas Aeruginosa and 3 Staphylococcus Epidermidis). Twelve eyes presented with proven fungal keratitis of Aspergillus species. Twelve different SDAS-OCT presentations of fungal and bacterial keratitis were found in this study. Our findings in fungal keratitis grasped two unique patterns of early localized and diffuse necrotic stromal cystic spaces.
CONCLUSION
SDAS-OCT imaging provided a range of characteristic patterns that could be used as an additional tool in diagnosis and management of bacterial and fungal microbial keratitis.
目的
研究微生物角膜炎（真菌性和细菌性角膜炎）的谱域眼前节光学相干断层扫描（SDAS-OCT）模式。
设计
前瞻性、横断面、观察性研究。
方法
对 20 例不同疾病阶段的确诊真菌性和细菌性微生物角膜炎患者的 20 只眼进行 SDAS-OCT 成像。
结果
8 只眼为确诊细菌性角膜炎（3 只为金黄色葡萄球菌、2 只为绿脓假单胞菌和 3 只为表皮葡萄球菌）。12 只眼为确诊的曲霉菌属真菌性角膜炎。本研究发现了 12 种不同的真菌和细菌性角膜炎的 SDAS-OCT 表现。我们在真菌性角膜炎中的发现抓住了两个早期局限性和弥漫性坏死性基质囊性空间的独特模式。
结论
SDAS-OCT 成像提供了一系列特征性模式，可作为诊断和治疗细菌性和真菌性微生物角膜炎的附加工具。
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