Wolman S R, Campbell M, Marchi M L, Deutsch S I, Gershon T D
Michigan Cancer Foundation, Detroit.
J Am Acad Child Adolesc Psychiatry. 1990 Nov;29(6):878-84. doi: 10.1097/00004583-199011000-00006.
Dermatoglyphic patterns formed during fetal development reflect genetic or early developmental events. These patterns might provide a means for investigation of a biological basis for autism, but the results of prior studies are not conclusive. The authors undertook a study of 95 autistic children, defined by DSM-III criteria ascertained independently by three child psychiatrists. The dermatoglyphic patterns of these children were compared with several control groups, all age-matched, separated by sex, and comprising different ethnic compositions. Analysis of variance as well as chi-square methods of statistical analysis were applied. Consistency among hands, ATD angle values, total ridge counts, incidence and effects on ridge count of arches, double loops, and whorls were evaluated in this comparatively large, well-controlled group of autistic children, and all failed to support a value for dermatoglyphic analysis as a discriminant of autism.
胎儿发育过程中形成的皮纹模式反映了遗传或早期发育事件。这些模式可能为研究自闭症的生物学基础提供一种方法，但先前研究的结果并不确凿。作者对95名自闭症儿童进行了研究，这些儿童由三位儿童精神科医生独立根据《精神疾病诊断与统计手册》第三版标准确定。将这些儿童的皮纹模式与几个对照组进行比较，所有对照组均按年龄匹配、按性别分开且包括不同的种族构成。应用了方差分析以及卡方统计分析方法。在这个规模较大、控制良好的自闭症儿童群体中，评估了双手之间的一致性、轴三叉角度值、总嵴数、弓型、双箕斗和螺纹的发生率及其对嵴数的影响，所有这些均未能支持皮纹分析作为自闭症判别指标的价值。
