Tahan S, Medeiros E H, Wehba J
Disciplina de Gastroenterologia Pediátrica Universidade Federal de São Paulo, Escola Paulista de Medicina-EPM-UNIFESP.
Arq Gastroenterol. 1997 Jul-Sep;34(3):196-204.
In 1990 a project was performed in Israel in which the authors reported a higher frequency of whorls and a lower frequency of ulnar loops in the dermatoglyphic pattern of children with celiac disease than in children belonging to control group. Based on these findings we carried out a similar study with our local population. Thirty six celiac children, their parents and siblings had their fingerprints analysed and compared to a control group matching for age, sex and race, in order to assess the efficiency of this method for the diagnosis of celiac disease. A statistically significant higher frequency of whorls and arches was found in celiac children than in control group (whorls = 40.6%, arches = 11.7%; whorls = 30.3%, arches = 5.0%, respectively) as well as a strong correlation between the dermatoglyphic pattern of the parents and their celiac children. There was also a statistically higher frequency of whorls > = 4 in celiac children (55.6%) than in controls (30.6%). The conclusion is that the dermatoglyphic pattern analysis can be used as a complementary data. Due to its low sensitivity (55.6%) and specificity (69.4%) considering the presence of four or more whorls, it is not useful as a screening or as a method itself, for the diagnosis of celiac disease.
1990年，以色列开展了一个项目，项目作者报告称，患有乳糜泻的儿童的皮纹模式中，斗形纹出现频率较高，而尺侧箕形纹出现频率较低，与对照组儿童相比存在差异。基于这些发现，我们对本地人群进行了一项类似的研究。36名乳糜泻儿童及其父母和兄弟姐妹接受了指纹分析，并与年龄、性别和种族相匹配的对照组进行比较，以评估这种方法对乳糜泻诊断的有效性。结果发现，乳糜泻儿童中斗形纹和弓形纹的出现频率在统计学上显著高于对照组（斗形纹分别为40.6%和30.3%，弓形纹分别为11.7%和5.0%），并且父母的皮纹模式与患乳糜泻的子女之间存在很强的相关性。此外，乳糜泻儿童中斗形纹≥4个的出现频率在统计学上也高于对照组（55.6%对30.6%）。结论是，皮纹模式分析可作为补充数据。考虑到出现四个或更多斗形纹时其敏感性较低（55.6%）和特异性较低（69.4%），它作为乳糜泻诊断的筛查方法或独立诊断方法并无用处。
