Lebedev V S, Veselovskiĭ A V, Fedorov Iu I
Izv Akad Nauk SSSR Biol. 1990 Sep-Oct(5):782-5.
Effect of Cu2+ on E. coli respiration and the role of oxygen in toxic action of copper has been studied. Stimulation of respiration is observed at initial time after introduction of Cu2+. It is based on a nonspecific cell response to membrane damage. After finishing of transitory processes, Cu2+ influenced respiration by noncompetitive inhibition, i.e. copper-sensitive enzyme can be oxygenated or nonoxygenated, and only the latter form of the enzyme is inhibited.
