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Acute water intoxication after intranasal desmopressin in a patient with primary polydispsia.

作者信息

Ferrer J, Halperin I, Conget J I, Cabrer J, Esmatjes E, Vilardell E

机构信息

Endocrinology and Nutrition Service, Hospital Clinic i Provincial, University of Barcelona, Spain.

出版信息

J Endocrinol Invest. 1990 Sep;13(8):663-6. doi: 10.1007/BF03349590.

Abstract

Only a few cases of severe acute water intoxication (AWI) due to intranasal desmopressin have been reported, none of which occurred in patients with primary polydipsia. We describe a case of AWI with semicoma and convulsions, due to intranasal desmopressin, in a 32-year-old patient with dipsogenic diabetes insipidus. Previous reported cases of AWI due to desmopressin are discussed. The importance of ruling out primary polydipsia when this drug is used, not only for central diabetes insipidus but also for other current indications such as classic hemophilia, is stressed.

摘要

相似文献

1
Acute water intoxication after intranasal desmopressin in a patient with primary polydispsia.
J Endocrinol Invest. 1990 Sep;13(8):663-6. doi: 10.1007/BF03349590.

本文引用的文献

1
Psychogenic polydipsia and inappropriate antidiuresis.
Arch Intern Med. 1980 Dec;140(12):1574.
4
Desmopressin.去氨加压素
Ann Intern Med. 1985 Aug;103(2):228-39. doi: 10.7326/0003-4819-103-2-228.
6
Psychosis and water balance.精神病与水平衡。
N Engl J Med. 1988 Feb 18;318(7):441-2. doi: 10.1056/NEJM198802183180708.
7
Polydipsia and hyponatremia in psychiatric patients.精神科患者的烦渴与低钠血症
Am J Psychiatry. 1988 Jun;145(6):675-83. doi: 10.1176/ajp.145.6.675.

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