一名因夜间遗尿症而服用去氨加压素的儿童出现癫痫发作并伴有低钠血症。

Seizure with hyponatremia in a child prescribed desmopressin for nocturnal enuresis.

作者信息

Yaouyanc G, Jonville A P, Yaouyanc-Lapalle H, Barbier P, Dutertre J P, Autret E

机构信息

Department of Medicine, Hôpital du Blanc, France.

出版信息

J Toxicol Clin Toxicol. 1992;30(4):637-41. doi: 10.3109/15563659209017947.

DOI:10.3109/15563659209017947

PMID:1433432

Abstract

We report a case of hyponatremia associated with a grand mal seizure in a 28 month-old child after intra-nasal desmopressin administration for high fluid intake with nocturnal enuresis. In view of the temporary symptomatic action and the seriousness of certain side-effects of desmopressin we recommend that desmopressin be used with caution in childhood enuresis.

摘要

我们报告了一例28个月大的儿童，在因夜间遗尿症高液体摄入量而经鼻给予去氨加压素后，出现与癫痫大发作相关的低钠血症。鉴于去氨加压素的暂时对症作用和某些副作用的严重性，我们建议在儿童遗尿症中谨慎使用去氨加压素。