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原发性内镜下泪囊鼻腔吻合术联合(或不联合)硅胶管:一项前瞻性随机研究。

Primary endoscopic dacryocystorhinostomy with or without silicone tubing: a prospective randomized study.

机构信息

Department of Ear, Nose, Throat and Head and Neck Surgery, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

出版信息

Am J Rhinol Allergy. 2012 Jul-Aug;26(4):332-4. doi: 10.2500/ajra.2012.26.3789. Epub 2012 Jun 21.

Abstract

BACKGROUND

Endoscopic dacryocystorhinostomy (DCR) is an effective surgical procedure to treat saccal and postsaccal stenosis or nasolacrimal duct obstruction. The use of silicone tube after endoscopic DCR is still controversial. A prospective randomized study was conducted to compare the success rate between the use of silicone stent and no use of silicone stent in endoscopic DCR.

METHODS

A prospective randomized study was conducted at Aseer Central Hospital and Abha Private Hospital, Abha, Kingdom of Saudi Arabia, on all patients undergoing endoscopic DCR between July 1, 2006 and 30 June 30, 2010. Patients were allocated randomly for endoscopic DCR with or without stent. The data collection included age, sex, diagnosis, method, and duration of surgery. Patients were followed up postoperatively at 1 week, 1 month, and then every 3 months for 1 year.

RESULTS

During the period of the study a total of 173 cases of postsaccal stenosis underwent endoscopic DCR (67 male and 106 female subjects). The mean age was 51.8 years (range, 18-72 years). A stent was used in 92 patients (53.2%) and not used in 81 patients (46.8%). With silicone tubing the success rate was 96%, and without silicone tubing it was 91%, an overall success rate of 94%. The odds ratio of failure without a silicone tube was 3.25 but confidence interval was from 0.84 to 12.60 and the difference between these two groups was statistically not significant (p = 0.117).

CONCLUSION

In this study, there was no statistically significant advantage of using endoscopic DCR with stent over the endoscopic DCR without stent.

摘要

背景

经内镜鼻腔泪囊吻合术(DCR)是治疗囊状和囊后狭窄或鼻泪管阻塞的有效手术方法。内镜 DCR 后使用硅胶管仍然存在争议。本研究旨在对比内镜 DCR 中使用和不使用硅胶支架的成功率。

方法

本前瞻性随机研究于 2006 年 7 月 1 日至 2010 年 6 月 30 日在沙特阿拉伯阿西尔中央医院和阿巴私人医院进行,纳入所有接受内镜 DCR 的患者。患者随机分为内镜 DCR 联合支架组和内镜 DCR 不联合支架组。收集的数据包括年龄、性别、诊断、手术方法和手术时间。术后 1 周、1 个月和之后每 3 个月随访 1 年。

结果

研究期间,共 173 例囊后狭窄患者接受了内镜 DCR(67 例男性,106 例女性)。平均年龄为 51.8 岁(范围:18-72 岁)。92 例患者(53.2%)使用了硅胶支架,81 例患者(46.8%)未使用硅胶支架。使用硅胶管的成功率为 96%,不使用硅胶管的成功率为 91%,总成功率为 94%。不使用硅胶管的失败风险比为 3.25,但置信区间为 0.84-12.60,两组间差异无统计学意义(p=0.117)。

结论

本研究中,内镜 DCR 联合支架与不联合支架相比,在统计学上没有明显优势。

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