运动训练诱导的线粒体质量调控。
Exercise training-induced regulation of mitochondrial quality.
机构信息
Departments of Medicine and Pharmacology, Center for Skeletal Muscle Research at Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA.
出版信息
Exerc Sport Sci Rev. 2012 Jul;40(3):159-64. doi: 10.1097/JES.0b013e3182575599.
Abstract
Mitochondria are dynamic organelles in skeletal muscle critical in physical performance and disease. The mitochondrial life cycle spans biogenesis, maintenance, and clearance. Exercise training may promote each of these processes, conferring positive impacts on skeletal muscle contractile and metabolic functions. This review focuses on the regulation of these processes by endurance exercise and discusses potential benefits in health and disease.
摘要
线粒体是骨骼肌中具有动态特征的细胞器，对于身体机能和疾病至关重要。线粒体的生命周期包括生物发生、维持和清除。运动训练可能会促进这些过程，对骨骼肌的收缩和代谢功能产生积极影响。本文重点讨论了耐力运动对这些过程的调节，并探讨了其在健康和疾病方面的潜在益处。
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