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糖尿病妊娠中胎盘的组织病理学考量

Histopathological considerations of placenta in pregnancy with diabetes.

作者信息

Gheorman Lavinia, Pleşea I E, Gheorman V

机构信息

Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.

出版信息

Rom J Morphol Embryol. 2012;53(2):329-36.

PMID:22732802
Abstract

The authors present the results of a study on 19 cases of pregnant women with diabetes who delivered in No. 1 Clinic of Obstetrics and Gynecology, Emergency County Hospital of Craiova, between October 1st, 2009 and September 1st, 2011. After delivery, placentas were harvested for the pathology study. The results of this study reveal: villous immaturity, villous edema, presence of basement membrane thickening, congestion of capillaries called "chorangiosis", intra- and extravillous fibrinoid and a deposit of glycogen. The authors state that although these lesions are not pathognomonic for pregnancy with diabetes, they are very suggestive and specific for this association: diabetes-pregnancy.

摘要

作者介绍了一项针对19例糖尿病孕妇的研究结果,这些孕妇于2009年10月1日至2011年9月1日期间在克拉约瓦县急诊医院第一妇产科诊所分娩。分娩后,采集胎盘进行病理学研究。该研究结果显示:绒毛不成熟、绒毛水肿、基底膜增厚、毛细血管充血(称为“绒毛膜血管病”)、绒毛内和绒毛外纤维素样物质以及糖原沉积。作者指出,尽管这些病变并非糖尿病妊娠所特有,但它们对糖尿病与妊娠的关联具有很强的提示性和特异性。

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Histopathological considerations of placenta in pregnancy with diabetes.糖尿病妊娠中胎盘的组织病理学考量
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Cureus. 2020 Oct 24;12(10):e11130. doi: 10.7759/cureus.11130.
2
Reduced Uteroplacental Perfusion Pressure (RUPP) causes altered trophoblast differentiation and pericyte reduction in the mouse placenta labyrinth.低子宫胎盘灌注压(RUPP)导致小鼠胎盘绒毛膜中滋养层分化和周细胞减少。
Sci Rep. 2018 Nov 21;8(1):17162. doi: 10.1038/s41598-018-35606-x.
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Histopathological study with immunohistochemical expression of vascular endothelial growth factor in placentas of hyperglycemic and diabetic women.
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J Lab Physicians. 2017 Oct-Dec;9(4):227-233. doi: 10.4103/JLP.JLP_148_16.
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Histopathological, Ultrastructural and Apoptotic Changes in Diabetic Rat Placenta.糖尿病大鼠胎盘的组织病理学、超微结构和细胞凋亡变化。
Balkan Med J. 2015 Jul;32(3):296-302. doi: 10.5152/balkanmedj.2015.15290. Epub 2015 Jul 1.
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Placental histomorphometry in gestational diabetes mellitus: the relationship between subsequent type 2 diabetes mellitus and race/ethnicity.妊娠糖尿病患者的胎盘组织形态计量学:种族/民族与 2 型糖尿病发病风险之间的关系。
Am J Clin Pathol. 2014 Apr;141(4):587-92. doi: 10.1309/AJCPX81AUNFPOTLL.