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结膜浸润性鳞状细胞癌

[Invasive squamous cell carcinoma of the conjunctiva].

作者信息

Arend N, Decker C, Messmer E M, Kampik A, Hintschich C

机构信息

Augenklinik der LMU, Klinikum der Universität München, Campus Innenstadt, Mathildenstr. 8, 80336 München.

出版信息

Ophthalmologe. 2013 Jan;110(1):57-60. doi: 10.1007/s00347-012-2578-z.

DOI:10.1007/s00347-012-2578-z
PMID:22733285
Abstract

We report the case of a 71-year-old male who was first diagnosed with conjunctival squamous cell carcinoma in September 2010. The lesion was excised twice and cryotherapy of the margins was performed. On histology the margins were not tumor-free but this was not followed up by further excision. After 5 months the patient was referred to this department with a growing tumor mass which had infiltrated into the anterior chamber and partly destroyed the iris. Because of this advanced finding extended enucleation was performed. The histological examination showed a well differentiated squamous cell carcinoma and no evidence of metastasis in lymph nodes or elsewhere could be found by conventional computed tomography (CT) and positron emission CT (PET-CT).

摘要

我们报告了一例71岁男性患者,其于2010年9月首次被诊断为结膜鳞状细胞癌。病变组织被切除两次,并对切缘进行了冷冻治疗。组织学检查显示切缘并非无肿瘤,但未进一步进行切除。5个月后,该患者因肿瘤肿块增大被转诊至我科,肿瘤已浸润至前房并部分破坏虹膜。鉴于这一进展性发现,遂行扩大眼球摘除术。组织学检查显示为高分化鳞状细胞癌,通过传统计算机断层扫描(CT)和正电子发射断层扫描(PET-CT)未发现淋巴结或其他部位有转移迹象。

相似文献

1
[Invasive squamous cell carcinoma of the conjunctiva].结膜浸润性鳞状细胞癌
Ophthalmologe. 2013 Jan;110(1):57-60. doi: 10.1007/s00347-012-2578-z.
2
Invasive squamous cell carcinoma of the conjunctiva.结膜浸润性鳞状细胞癌。
Bull Soc Belge Ophtalmol. 2000(278):43-7.
3
Deeply invasive squamous cell carcinoma of the conjunctiva: case report.
Int Ophthalmol. 1990 Jul;14(4):241-4. doi: 10.1007/BF00159858.
4
Corneal-conjunctival squamous cell carcinoma.角膜结膜鳞状细胞癌
Cornea. 2008 Sep;27(8):957-8. doi: 10.1097/ICO.0b013e31816f5ef2.
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The 1998 Pan American Lecture. Intraocular invasion of conjunctival squamous cell carcinoma in five patients.1998年泛美讲座。5例结膜鳞状细胞癌的眼内侵犯
Ophthalmic Plast Reconstr Surg. 1999 May;15(3):153-60. doi: 10.1097/00002341-199905000-00003.
6
Plaque radiotherapy in the management of scleral-invasive conjunctival squamous cell carcinoma: an analysis of 15 eyes.敷贴放疗在巩膜浸润性结膜鳞状细胞癌治疗中的应用:15例眼分析
JAMA Ophthalmol. 2014 Jun;132(6):691-6. doi: 10.1001/jamaophthalmol.2014.86.
7
Massive precorneal extension of squamous cell carcinoma of the conjunctiva.结膜鳞状细胞癌的角膜前巨大延伸。
Cornea. 1993 Nov;12(6):537-40. doi: 10.1097/00003226-199311000-00013.
8
[Intraocular invasion of melanoma of the conjunctiva].
Klin Monbl Augenheilkd. 1999 Dec;215(6):370-2. doi: 10.1055/s-2008-1034735.
9
Long-term results of cryotherapy on malignant epithelial tumors of the conjunctiva.
Am J Ophthalmol. 1989 Apr 15;107(4):337-40. doi: 10.1016/0002-9394(89)90655-7.
10
Microscopically controlled excision of conjunctival squamous cell carcinoma.结膜鳞状细胞癌的显微镜控制下切除术。
Am J Ophthalmol. 1994 Jan 15;117(1):97-102. doi: 10.1016/s0002-9394(14)73021-1.

本文引用的文献

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Squamous carcinoma of the conjunctiva.结膜鳞状细胞癌
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Subconjunctival/perilesional recombinant interferon α2b for ocular surface squamous neoplasia: a 10-year review.结膜下/病变周围重组干扰素 α2b 治疗眼表面鳞状上皮肿瘤:10 年回顾。
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Human papillomavirus infection and squamous cell carcinoma of the conjunctiva.人乳头瘤病毒感染与结膜鳞状细胞癌。
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J Fr Ophtalmol. 2009 Dec;32(10):707-14. doi: 10.1016/j.jfo.2009.10.016.
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No evidence for a pathogenic role of human papillomavirus infection in ocular surface squamous neoplasia in Germany.在德国,没有证据表明人乳头瘤病毒感染在眼表鳞状上皮肿瘤中起致病作用。
Curr Eye Res. 2009 Aug;34(8):666-71. doi: 10.1080/02713680903007162.
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Topical treatment options for conjunctival neoplasms.结膜肿瘤的局部治疗选择。
Clin Ophthalmol. 2008 Sep;2(3):503-15. doi: 10.2147/opth.s1606.
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Intraepithelial and invasive squamous neoplasms of the conjunctiva in Ibadan, Nigeria: a clinicopathological study of 46 cases.
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