结膜鳞状细胞癌的角膜前巨大延伸。

Massive precorneal extension of squamous cell carcinoma of the conjunctiva.

作者信息

Cha S B, Shields C L, Shields J A, Eagel R C, De Potter P, Talansky M

机构信息

Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.

出版信息

Cornea. 1993 Nov;12(6):537-40. doi: 10.1097/00003226-199311000-00013.

DOI:10.1097/00003226-199311000-00013

PMID:8261787

Abstract

A 73-year-old man had only light perception vision from a slowly enlarging fleshy papillomatous mass covering the entire cornea. The lesion was excised completely, leaving a clear corneal bed and 20/25 vision. Histopathologically, the lesion was found to be squamous cell carcinoma in situ with early microinvasion of the basement membrane. Viral studies for human papilloma virus were negative. This case represents a massive superficial involvement of the cornea by squamous cell carcinoma and shows the resistance of Bowman's membrane to tumor penetration.

摘要

一名73岁男性因一个逐渐增大的肉质乳头状肿物覆盖整个角膜而仅存光感视力。该病变被完全切除，留下清晰的角膜床，视力恢复到20/25。组织病理学检查发现，该病变为原位鳞状细胞癌，伴有基底膜早期微浸润。人乳头瘤病毒的病毒学研究结果为阴性。该病例代表了鳞状细胞癌对角膜的广泛浅表侵犯，并显示了Bowman膜对肿瘤浸润的抵抗作用。