Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA.
AJR Am J Roentgenol. 2012 Jul;199(1):W65-73. doi: 10.2214/AJR.11.7798.
The purpose of this study was to assess the radiation dose distribution and image quality for organ-based dose modulation during adult thoracic MDCT.
Organ doses were measured using an anthropomorphic adult female phantom containing 30 metal oxide semiconductor field-effect transistor detectors on a dual-source MDCT scanner with two protocols: standard tube current modulation thoracic CT and organ-based dose modulation using a 120° radial arc. Radiochromic film measured the relative axial dose. Noise was measured to evaluate image quality. Breast tissue location across the anterior aspect of the thorax was retrospectively assessed in 100 consecutive thoracic MDCT examinations.
There was a 17-47% decrease (p = < 0.05) in anterior thoracic organ dose and a maximum 52% increase (p = < 0.05) in posterior thoracic organ dose using organ-based dose modulation compared with tube current modulation. Effective dose (SD) for tube current modulation and organ-based dose modulation were 5.25 ± 0.36 mSv and 4.42 ± 0.30 mSv, respectively. Radiochromic film analysis showed a 30% relative midline anterior-posterior gradient. There was no statistically significant difference in image noise. Adult female breast tissue was located within an average anterior angle of 155° (123-187°).
Organ-based dose modulation CT using an anterior 120° arc can reduce the organ dose in the anterior aspect of the thorax with a compensatory organ dose increase posteriorly without impairment of image quality. Laterally located breast tissue will have higher organ doses than medially located breast tissue when using organ-based dose modulation. The benefit of this dose reduction must be clinically determined on the basis of the relationship of the irradiated organs to the location of the prescribed radial arc used in organ-based dose modulation.
本研究旨在评估成人胸部多层 CT 中基于器官剂量调制的剂量分布和图像质量。
使用包含 30 个金属氧化物半导体场效应晶体管探测器的成人女性体模,在双源 MDCT 扫描仪上进行两种方案的器官剂量测量:标准管电流调制胸部 CT 和基于器官剂量调制,使用 120° 径向弧形。放射色胶片测量相对轴向剂量。测量噪声以评估图像质量。回顾性评估了 100 例连续胸部 MDCT 检查中胸部前部的乳腺组织位置。
与管电流调制相比,基于器官剂量调制可使前胸部器官剂量降低 17%-47%(p<0.05),后胸部器官剂量最大增加 52%(p<0.05)。管电流调制和基于器官剂量调制的有效剂量(SD)分别为 5.25±0.36 mSv 和 4.42±0.30 mSv。放射色胶片分析显示中线前-后 30%的相对梯度。图像噪声无统计学差异。成年女性乳腺组织位于平均前角 155°(123-187°)。
使用前 120°弧形的基于器官剂量调制 CT 可以降低胸部前部的器官剂量,同时在后部补偿性地增加器官剂量,而不会损害图像质量。使用基于器官剂量调制时,位于外侧的乳腺组织的器官剂量将高于位于内侧的乳腺组织的器官剂量。这种剂量减少的益处必须根据受照射器官与基于器官剂量调制中使用的规定弧形位置的关系,从临床角度确定。