From the Department of Radiology, Hôpital André Vésale, Montignies-le-Tilleul, Belgium (S.T.); Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (D.E.L., M.S., A.A.B.); Department of Radiology, Hôpital Erasme, Brussels, Belgium (P.A.G.); and Department of Radiology, Epicura-Clinique Louis Caty, Rue Louis Caty 136, B-7331 Baudour, Belgium (D.T.).
Radiology. 2015 Jan;274(1):260-6. doi: 10.1148/radiol.14140694. Epub 2014 Aug 22.
To retrospectively determine the potential of organ-based tube current modulation ( OBTCM organ-based tube current modulation ) to reduce the radiation dose delivered to breast tissue by computed tomography (CT) by determining breast angular position in relation to the zones of decreased versus increased radiation.
The authors obtained institutional review board approval for this study and patients' written informed consent. In two academic centers (center A: Beth Israel Deaconess Medical Center, Boston, Mass; and center B: Hôpital André Vésale, Montignies-le-Tilleul, Belgium), data were collected from clinical thoracic CT examinations performed in 498 women (mean age, 60 years; age range, 18-95 years) in the supine position and 34 women (mean age, 53 years; age range, 18-84 years) in the prone position. One radiologist in each center determined breast tissue location and measured its inner and outer boundaries with respect to the isocenter of the CT examination. The percentages of women with breast tissue within and those with breast tissue outside the zone of decreased radiation delivered by OBTCM organ-based tube current modulation were determined. The location of breast tissue was correlated with patient age and with sagittal and coronal diameters of the thorax by using the Student t test, Fisher exact test, and Pearson correlation.
None of the women lying in the supine position had the entirety of the breast tissue located within the reduced-dose zone. Breast tissue was located in the increased-dose zone in 99% of women lying supine and in 82% of women lying prone.
The breast angular position of almost all women was higher than the angular limit of the reduced versus the increased dose in OBTCM organ-based tube current modulation . No woman, regardless of supine or prone position, had all breast tissue within the reduced-dose zone.
通过确定与减少与增加辐射相对应的区域相比，乳房在角度上的位置，来回顾性地确定基于器官的管电流调制（OBTCM 基于器官的管电流调制）降低 CT 检查中乳房组织接受的辐射剂量的潜力。
作者获得了该研究的机构审查委员会批准和患者的书面知情同意。在两个学术中心（中心 A：波士顿贝斯以色列女执事医疗中心；中心 B：比利时蒙蒂尼耶勒蒂勒尔的安德烈·维塞尔医院），从 498 名女性（平均年龄 60 岁；年龄范围 18-95 岁）的仰卧位和 34 名女性（平均年龄 53 岁；年龄范围 18-84 岁）的俯卧位进行的临床胸部 CT 检查中收集数据。每个中心的一名放射科医生确定乳房组织的位置，并测量其相对于 CT 检查等中心点的内边界和外边界。确定了乳房组织位于 OBTCM 基于器官的管电流调制的减少辐射剂量区域内和位于该区域外的女性百分比。使用 Student t 检验、Fisher 确切检验和 Pearson 相关性，将乳房组织的位置与患者年龄以及胸廓的矢状和冠状直径相关联。
没有一名仰卧位的女性的整个乳房组织都位于降低剂量区域内。99%的仰卧位女性和 82%的俯卧位女性的乳房组织位于增加剂量区域。
几乎所有女性的乳房角度位置都高于 OBTCM 基于器官的管电流调制中减少与增加剂量的角度限制。无论仰卧位还是俯卧位，没有女性的所有乳房组织都位于降低剂量区域内。
