Seiler Gabriela S, Robertson Ian D, Mai Wilfried, Widmer William R, Suran Jantra, Nemanic Sarah, Lamb Christopher R, Lang Johann, Johnson Jeffrey L, Thrall Donald E
Department of Molecular Biomedical Sciences, North Carolina State University, 1052 William Moore Drive, Raleigh, NC 27607, USA.
Vet Radiol Ultrasound. 2012 Mar-Apr;53(2):157-61. doi: 10.1111/j.1740-8261.2011.01893.x.
Single-shot turbo spin-echo sequences are heavily T2-weighted sequences that are exceptionally well suited to evaluate the subarachnoid space. In the T2-weighted fast spin-echo sequences that are used routinely in spinal magnetic resonance (MR) imaging, the subarachnoid space is not well differentiated from the surrounding epidural fat, which could lead to decreased detection of lesions of the subarachnoid space such as arachnoid diverticula. Our purpose was to determine the added value of a single-shot turbo spin-echo sequence in identifying cystic lesions of the subarachnoid space in dogs. MR images of six dogs with a confirmed arachnoid diverticulum and 24 dogs with other spinal disease were included. Six observers were asked to interpret only T2-weighted images initially, and in a second session, T2-weighted and half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequences. The MR images were anonymized, and no signalment, history, or clinical information was provided. Without the HASTE sequences, 25% of arachnoid diverticula were identified. Adding the HASTE sequence increased the diagnosis of arachnoid diverticulum to 52.8%. The resulting difference, after adding the HASTE sequence, of 27.8% was statistically significant (P = 0.002). No false-positive diagnoses of arachnoid diverticulum were made with either sequence. Although sensitivity in this study was likely artificially low, the significantly increased detection rate of arachnoid diverticula when using HASTE imaging indicates that this sequence is a valuable addition to MR imaging protocols for the canine spine.
单次激发快速自旋回波序列是重T2加权序列,非常适合评估蛛网膜下腔。在脊柱磁共振成像中常规使用的T2加权快速自旋回波序列中,蛛网膜下腔与周围硬膜外脂肪的区分不佳,这可能导致蛛网膜下腔病变(如蛛网膜憩室)的检出率降低。我们的目的是确定单次激发快速自旋回波序列在识别犬蛛网膜下腔囊性病变中的附加价值。纳入了6只确诊为蛛网膜憩室的犬和24只患有其他脊柱疾病的犬的磁共振图像。最初要求6名观察者仅解读T2加权图像,在第二阶段解读T2加权和半傅里叶采集单次激发快速自旋回波(HASTE)序列图像。磁共振图像进行了匿名处理,未提供动物特征、病史或临床信息。在没有HASTE序列的情况下,25%的蛛网膜憩室被识别出来。添加HASTE序列后,蛛网膜憩室的诊断率提高到了52.8%。添加HASTE序列后产生的27.8%的差异具有统计学意义(P = 0.002)。两种序列均未出现蛛网膜憩室的假阳性诊断。尽管本研究中的敏感性可能人为偏低,但使用HASTE成像时蛛网膜憩室的检出率显著提高,表明该序列是犬脊柱磁共振成像方案中的一个有价值的补充。