Tinetti Matias, Costello Ramiro, Cardenas Cesar, Piazza Antonio, Iglesias Ricardo, Baranchuk Adrian
Cardiology Division Cardiovascular Surgery, Sanatorio de la Trinidad Mitre, Sanatorio de la Trinidad Palermo, Buenos Aires, Argentina.
Pacing Clin Electrophysiol. 2012 Aug;35(8):999-1004. doi: 10.1111/j.1540-8159.2012.03458.x. Epub 2012 Jun 26.
MAZE IV surgery is effective in restoring sinus rhythm (SR) and atrial contraction (AC) in patients with nonrheumatic persistent atrial fibrillation (AF). However, there is less information on its effectiveness to restore AC in patients with rheumatic disease.
To assess the effectiveness of the MAZE IV surgery in restoring AC in patients with rheumatic disease and long persistent AF.
Prospective, consecutive study in patients who underwent cardiovascular surgery and had long persistent AF in whom MAZE IV surgery was performed. The presence of AC was assessed by lateral mitral annulus tissue Doppler.
A total of 75 patients were included. Mean age 60 years (±11.7); 27 men (36%). AF duration was 63 months (±34.1). Primary indication for surgery: rheumatic mitral stenosis 67 patients and mitral insufficiency eight patients. Mean left ventricular ejection fraction (LVEF) was 51.8% (±12.1) and mean left atrial area was 37 cm(2) (±10.3). After a mean follow-up of 28 months (±9.3), 69 patients remained alive and 59 were in SR. AC was detected in 37.3% (Group A) and absent in 62.7% (Group B). The mean difference between groups was the high prevalence of AF longer than 5 years in group B (P = 0.000001). There were no differences related to left atrial size, LVEF, and age.
In patients with rheumatic disease, the absence of correlation between SR recovery and AC recovery post MAZE IV surgery is significant. A history of long persistent AF lasting more than 5 years was a strong predictor for the absence of AC.
迷宫IV手术对于恢复非风湿性持续性心房颤动(AF)患者的窦性心律(SR)和心房收缩(AC)有效。然而,关于其恢复风湿性疾病患者AC有效性的信息较少。
评估迷宫IV手术恢复风湿性疾病合并长期持续性AF患者AC的有效性。
对接受心血管手术且患有长期持续性AF并接受迷宫IV手术的患者进行前瞻性、连续性研究。通过二尖瓣环外侧组织多普勒评估AC的存在情况。
共纳入75例患者。平均年龄60岁(±11.7);男性27例(36%)。AF持续时间为63个月(±34.1)。手术的主要适应证:风湿性二尖瓣狭窄67例,二尖瓣关闭不全8例。平均左心室射血分数(LVEF)为51.8%(±12.1),平均左心房面积为37 cm²(±10.3)。平均随访28个月(±9.3)后,69例患者存活,59例处于SR状态。37.3%的患者检测到AC(A组),62.7%的患者未检测到AC(B组)。两组之间的平均差异在于B组AF持续时间超过5年的患病率较高(P = 0.000001)。在左心房大小、LVEF和年龄方面无差异。
在风湿性疾病患者中,迷宫IV手术后SR恢复与AC恢复之间缺乏相关性具有显著性。持续时间超过5年的长期持续性AF病史是AC缺失的有力预测因素。