Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Fitoterapia. 2012 Oct;83(7):1242-7. doi: 10.1016/j.fitote.2012.06.009. Epub 2012 Jun 23.
Phytochemical investigation of the ethanol extract of Euphorbia kansuensis Proch. led to the isolation of three new triterpenoids, along with ten known compounds. Their structures were established by extensive 1D and 2D NMR, as well as other spectrum analysis. Biological activities of the three new compounds against Hela cell, Hep-G2 cell, C. albicans ATCC10231 cell and SC5314 cell were evaluated. They showed strong anti-tumor and moderate anti-inflammatory activities with MIC values ranging from 13 to 25 μg/ml and from 30 to 128 μg/ml.
对甘肃大戟（Euphorbia kansuensis Proch.）乙醇提取物进行植物化学研究，分离得到三种新的三萜类化合物，以及十种已知化合物。通过广泛的 1D 和 2D NMR 以及其他光谱分析确定了它们的结构。评估了三种新化合物对 Hela 细胞、Hep-G2 细胞、C. albicans ATCC10231 细胞和 SC5314 细胞的活性。它们表现出较强的抗肿瘤和适度的抗炎活性，MIC 值范围为 13 至 25 μg/ml 和 30 至 128 μg/ml。
