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铜催化的多米诺偶联反应:合成吲哚酮的有效方法。

Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles.

机构信息

Department of Chemistry, Tamkang University, New Taipei City, 25137, Taiwan, ROC.

出版信息

Org Biomol Chem. 2012 Aug 21;10(31):6404-9. doi: 10.1039/c2ob26110c. Epub 2012 Jun 26.

Abstract

An efficient and novel procedure for a copper catalyzed domino coupling reaction has been developed, which afforded various oxindoles in good to excellent yields with tolerance of various substituents. In addition, this method could be applied to synthesize horsfiline and coerulescine in few steps with high total yields.

摘要

发展了一种高效新颖的铜催化多组分偶联反应,该方法能以良好至优异的收率得到各种取代基的氧吲哚,此外,该方法可以几步高总收率合成horsfiline 和 coerulescine。

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