Berufsgenossenschaftliche Unfallklinik Murnau, Trauma Center, Prof. Küntscherstr. 8, 82418 Murnau, Germany.
Arch Orthop Trauma Surg. 2012 Oct;132(10):1473-80. doi: 10.1007/s00402-012-1576-6. Epub 2012 Jun 27.
Autologous bone graft is the gold standard for vertebral body replacement. Currently, after modern implants for vertebral body replacement are available, controversies exist regarding the optimal implant strategy.
Between 2002 and 2003, 17 patients were included in this study, all suffering from incomplete burst fractures of the thoracolumbar spine. All of them were treated by ventral monosegmental spondylodesis using iliac crest bone graft. The individual treatment strategy depended on the fracture situation and patient's condition. After an average of 74 months (range 66-84) a clinical and computer tomographic follow-up examination was performed in 14 patients (average age, 35.2 years) including VAS spine score and SF 36 score. Nine patients were treated ventral only five patients dorsoventrally.
Complete osseous consolidation was visible in nine, partial consolidation (>30 %) in four, and lysis in one patient, without any significant differences between ventral only or dorsoventral approach. After removal of the fixateur interne the level of consolidation improved in all patients, treated dorsoventrally. There was no significant correlation between percentage of osseous consolidation and the clinical follow-up parameters. After 6 years, 71 % of the patients suffered from persistent pain associated with the approach to the iliac crest. Two revision surgeries have been necessary.
High rates of osseous consolidation are visible 6 years after ventral spondylodesis by iliac crest bone grafts. A further improvement of consolidation can be expected after dorsal implant removal. But the surgical approach to the iliac crest is accompanied with a relevant complication rate.
自体骨移植是椎体置换的金标准。目前,现代椎体置换植入物出现后,对于最佳植入物策略仍存在争议。
在 2002 年至 2003 年间,本研究纳入了 17 例患有胸腰椎不完整爆裂骨折的患者。所有患者均采用髂嵴骨移植行前路单节段脊柱融合术治疗。具体的治疗策略取决于骨折情况和患者状况。在平均 74 个月(66-84 个月)的随访后,对 14 例患者(平均年龄 35.2 岁)进行了临床和计算机断层扫描检查,包括 VAS 脊柱评分和 SF-36 评分。9 例患者仅接受前路治疗,5 例患者接受前后路联合治疗。
9 例患者可见完全骨融合,4 例患者可见部分融合(>30%),1 例患者可见骨溶解,但前路或前后路治疗之间无明显差异。内固定器取出后,所有接受前后路治疗的患者融合水平均得到改善。骨融合率与临床随访参数之间无显著相关性。6 年后,71%的患者仍存在与取髂嵴相关的持续性疼痛。有 2 例患者需要进行翻修手术。
6 年后,采用髂嵴骨移植行前路脊柱融合术可获得较高的骨融合率。去除后路植入物后,可进一步提高融合率。但取髂嵴的手术入路会带来相关并发症。