Miyamura M, Xi L, Ishida K, Schena F, Cerretelli P
Research Center of Health, Physical Fitness and Sports, Nagoya University, Japan.
Jpn J Physiol. 1990;40(3):417-22. doi: 10.2170/jjphysiol.40.417.
In order to investigate the effects of acute hypoxia and accompanying hypocapnia on the ventilatory response at the onset of dynamic exercise, four healthy adult men performed 50W rectangular loads on a cycle-ergometer in normoxic (FIO2 = 0.21) and hypoxic (FIO2 = 0.11) conditions. No statistically significant differences in the initial ventilatory responses to exercise (both delta VI and delta VE assessed on a breath-by-breath basis) were found between eucapnic normoxia (PETO2 approximately 95, PETCO2 approximately 42 Torr) and hypocapnic hypoxia (PETO2 approximately 45, PETCO2 approximately 35 Torr). The present findings support the contention that the neurogenic ventilatory drive at the onset of early exercise is independent from PO2 and PCO2.
为了研究急性低氧和伴随的低碳酸血症对动态运动开始时通气反应的影响，四名健康成年男性在常氧（FIO2 = 0.21）和低氧（FIO2 = 0.11）条件下，在自行车测力计上进行50W的矩形负荷运动。在等碳酸常氧（PETO2约为95，PETCO2约为42 Torr）和低碳酸低氧（PETO2约为45，PETCO2约为35 Torr）之间，未发现对运动的初始通气反应（通过逐次呼吸评估的ΔVI和ΔVE）有统计学显著差异。目前的研究结果支持这样的观点，即早期运动开始时的神经源性通气驱动独立于PO2和PCO2。
