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急性低氧对人体周期性运动开始时通气反应的影响。

Effects of acute hypoxia on ventilatory response at the onset of cycle exercise in man.

作者信息

Miyamura M, Ishida K, Kobayashi T, Ohkuwa T, Itoh H

机构信息

Laboratory for Work Physiology, Research Center of Health, Physical Fitness and Sports, Nagoya University, Japan.

出版信息

Jpn J Physiol. 1992;42(5):823-9. doi: 10.2170/jjphysiol.42.823.

DOI:10.2170/jjphysiol.42.823
PMID:1491506
Abstract

In order to examine whether or not there are initial changes in ventilation at the start of bicycle exercise having work loads of differing intensities are affected with regard to normoxia and to hypoxia accompanying hypocapnia, six healthy male subjects performed submaximal exercise of 30 and 120 W at 60 rpm under normoxic (FIO2 = 0.21) and hypoxic (FIO2 = 0.11) conditions. Resting ventilation was significantly higher in hypoxia than in normoxia. However, no statistically significant differences in the initial change in ventilation at the start of exercise (delta VI assessed breath-by-breath) were found between eucapnic normoxia and hypocapnic hypoxia in both 30 and 120 W exercise. Moreover, blood lactate after exercise did not increase in any conditions as compared with rest. These observations suggest that the neurogenic ventilatory response immediately after submaximal exercise at a work load below the subject's anaerobic threshold is independent from PO2.

摘要

为了研究在常氧和伴有低碳酸血症的低氧条件下,不同强度工作负荷的自行车运动开始时通气是否有初始变化,六名健康男性受试者在常氧(FIO2 = 0.21)和低氧(FIO2 = 0.11)条件下以60转/分钟的速度进行了30瓦和120瓦的次最大运动。低氧时的静息通气显著高于常氧。然而,在30瓦和120瓦运动中,在常碳酸血症常氧和低碳酸血症低氧之间,运动开始时通气的初始变化(逐次呼吸评估的delta VI)没有发现统计学上的显著差异。此外,与休息相比,运动后任何条件下的血乳酸都没有增加。这些观察结果表明,在低于受试者无氧阈值的工作负荷下进行次最大运动后,神经源性通气反应与PO2无关。

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