Ariyoshi A, Sagiyama K, Hasuo K, Oshima K, Hiratsuka Y, Yamaguchi A, Fujisawa Y, Yoshida T, Tsuji Y, Komatsu K
Department of Urology, School of Medicine, Fukuoka University.
Nihon Hinyokika Gakkai Zasshi. 1990 Oct;81(10):1555-62. doi: 10.5980/jpnjurol1989.81.1555.
A series of 185 patients, 133 males and 52 females, were treated by ileal conduit urinary diversion in the past 17 years. The patients ranged in age from 7 months to 81 years with an average of 59 years. Diversions were performed for malignant diseases in 174 patients, 85% of whom underwent a simultaneous radical surgery. The follow-up covered the postoperative period from 4 months to 16 years 8 months with an average of 4 years 8 months. Six patients (3%) died within 1 month of operation, and 43 of a total of 58 mortal cases died of cancer thereafter. The survival rates of 143 patients with bladder cancer were 84% for 1 year, 72% for 3 years, 67% for 5 years, 62% for 10 years and 54% for 15 years. Early complications were noticed in 38% of the patients. Delayed wound healing due to local infection (20%) and intestinal obstruction (10%) were the two major complications in this period. Late complications were encountered in 51% of the patients. Mild peristomal dermatitis (22%) and gradually developing renal complications (22%) are two major problems in the standard ileal conduit urinary diversion. The latter was significantly more frequent in patients who underwent the operation between 1973 and 1981 than in those who had the surgery between 1982 and 1989. Postoperative hydronephrosis was observed in 15 (13%) of 117 patients who showed normal urograms preoperatively. Ileoureteral reflux was observed in 50% of the cases with nonobstructing conduits, while it increased up to 70% along with obstruction of the conduit.(ABSTRACT TRUNCATED AT 250 WORDS)
在过去17年中,对185例患者实施了回肠导管尿流改道术,其中男性133例,女性52例。患者年龄从7个月至81岁不等,平均年龄59岁。174例患者因恶性疾病接受改道术,其中85%同时接受了根治性手术。随访时间为术后4个月至16年8个月,平均4年8个月。6例患者(3%)在术后1个月内死亡,58例死亡病例中43例随后死于癌症。143例膀胱癌患者的1年生存率为84%,3年生存率为72%,5年生存率为67%,10年生存率为62%,15年生存率为54%。38%的患者出现早期并发症。此期间的两大主要并发症是因局部感染导致的伤口愈合延迟(20%)和肠梗阻(10%)。51%的患者出现晚期并发症。轻度造口周围皮炎(22%)和逐渐发展的肾脏并发症(22%)是标准回肠导管尿流改道术中的两大主要问题。1973年至1981年接受手术的患者中,后者的发生率明显高于1982年至1989年接受手术的患者。117例术前尿路造影正常的患者中,15例(13%)术后出现肾积水。在无梗阻导管的病例中,输尿管回肠反流的发生率为50%,而随着导管梗阻,其发生率增至70%。(摘要截选至250词)