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[新出现的心绞痛:脂质、脂蛋白以及载脂蛋白A1和B在缺血性心脏病预后中的作用]

[Newly manifested angina pectoris: role of lipids, lipoproteins and apoproteins A1 and B in the prognosis of ischemic heart disease].

作者信息

Kachalkov D V, Gratsianskiĭ N A, Deev A D, Nechaev A S

出版信息

Kardiologiia. 1990 Sep;30(9):44-8.

PMID:2273735
Abstract

In 151 patients with first angina, a prognostic value of various factors: lipids, lipo- and apoproteins AI and B was studied in relation to the development of clinical remission 1-1.5 years after the onset of the disease. In multifactorial discriminant analysis, the predictors of clinical remission turned out to be heart rate reached at the maximal exercise during bicycle ergometry, the number of diseased segments with any visible degrees of stenosis, the course of the disease within the first month, the number of diseased segments with 70% or more stenoses, the number of afflicted vessels with 70% or more stenoses, the power achieved during bicycle ergometry, high levels of high density lipoproteins, and age. A prognostic value of the same factors in poor prognosis (myocardial infarction or death) was examined in 124 out of 151 patients. The predictors proved to be low total cholesterol levels, the power achieved during bicycle ergometry, smoking, a history of smoking, the number of diseased segments with any visible degrees of stenosis, the number of diseased segments with 70% or more stenoses, and the conditions promoting the development of the first anginal episode.

摘要

在151例初发心绞痛患者中,研究了各种因素(脂质、脂蛋白和载脂蛋白AI及B)对疾病发作后1至1.5年临床缓解情况的预后价值。在多因素判别分析中,临床缓解的预测因素包括自行车测力计最大运动时达到的心率、有任何可见狭窄程度的病变节段数、疾病第一个月内的病程、狭窄程度达70%或更高的病变节段数、狭窄程度达70%或更高的受累血管数、自行车测力计运动时达到的功率、高密度脂蛋白水平高以及年龄。在151例患者中的124例中,研究了相同因素对预后不良(心肌梗死或死亡)的预后价值。结果证明预测因素为总胆固醇水平低、自行车测力计运动时达到的功率、吸烟、吸烟史、有任何可见狭窄程度的病变节段数、狭窄程度达70%或更高的病变节段数以及促发首次心绞痛发作的情况。

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Kardiologiia. 1990 Sep;30(9):44-8.
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