拟进行肝移植的肝硬化患者气体交换异常的演变
Evolution of gas exchange abnormalities in patients with liver cirrhosis candidate for liver transplantation.
作者信息
Ghayumi S M A, Mehrabi S, Hoseini Asl M
机构信息
Department of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Iran Red Crescent Med J. 2012 Mar;14(3):171-3. Epub 2012 Mar 1.
BACKGROUND
Hypoxemia is common in patients with cirrhosis but the natural history of this syndrome is unknown. This study was conducted to evaluate the natural history of arterial oxygenation in patient with end stage liver cirrhosis.
METHODS
Sixty eight patients with liver cirrhosis were followed up for 6-12 months. Arterial blood gas (ABG) and pulse oximetry were obtained on day of presentation and follow up.
RESULTS
There were no significant changes in the oxygen saturation by pulse oximetry (SpO2), partial pressure of oxygen (PaO2) and alveolar arterial oxygen gradient (A-a O2) after 6-12 months. Mean arterial oxygen saturation (SaO2) in 46 patients was 95.42±1.92, and after follow up changed to 95.45±2.96. Thirty eight patients had SaO2 > 94% (mean 96.12±1.08 after 6-12 months changed to 95.66±2.58) ; 8 patients had SaO2 = 94 (mean 92.08±1.44 after 6-12 months changed to 94.46±4.47).
CONCLUSION
There were no significant changes in the SpO2, PaO2 and A-a O2 after 6-12 months.
背景
低氧血症在肝硬化患者中很常见，但该综合征的自然病程尚不清楚。本研究旨在评估终末期肝硬化患者动脉氧合的自然病程。
方法
对68例肝硬化患者进行了6至12个月的随访。在就诊当天和随访时获取动脉血气（ABG）和脉搏血氧饱和度。
结果
6至12个月后，脉搏血氧饱和度（SpO2）、氧分压（PaO2）和肺泡动脉氧梯度（A-a O2）无显著变化。46例患者的平均动脉血氧饱和度（SaO2）为95.42±1.92，随访后变为95.45±2.96。38例患者的SaO2>94%（6至12个月后平均为96.12±1.08，变为95.66±2.58）；8例患者的SaO2 = 94（6至12个月后平均为92.08±1.44，变为94.46±4.47）。
结论
6至12个月后，SpO2、PaO2和A-a O2无显著变化。
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