Gonchar A M, Kogan A S, Troitskiĭ A V, Beliaev M D, Sokolov B N, Usov S A, Danilov D G
Khirurgiia (Mosk). 1990 Sep(9):69-73.
The authors discuss the results of application of proteinase preparations immobilized on a water soluble carrier (Immozymase) and a water insoluble carrier (Profezyme) in the management of ++pyo-necrotic processes of various etiology and localization in 1,059 patients. The wounds were cleansed 1.5-2 times quicker than with the traditional methods of treatment. Immobilized proteinases possessing a prolonged therapeutic effect were found to stimulate the regeneration process. The authors believe the use of Immozymase to be promising in the treatment of purulent foci which are drained with difficulty and in intracavitary administration for treating purulent processes in the thoracic or abdominal cavity.
作者讨论了固定在水溶性载体（免疫酶）和水不溶性载体（专业酶）上的蛋白酶制剂在1059例不同病因和部位的脓性坏死过程治疗中的应用结果。伤口清洁速度比传统治疗方法快1.5至2倍。发现具有延长治疗效果的固定化蛋白酶能刺激再生过程。作者认为免疫酶在治疗引流困难的化脓病灶以及胸腔或腹腔内给药治疗化脓性过程方面具有应用前景。
