Department of Oral and Maxillofacial Surgery, Loma Linda University School of Dentistry, Loma Linda, California 92350, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Feb;115(2):e1-6. doi: 10.1016/j.oooo.2011.09.033. Epub 2012 Jun 26.
Osteomas are benign slow-growing tumors. These lesions are essentially restricted to the craniofacial skeleton and rarely diagnosed in other bones. The etiology is often multifactorial. It could be genetic or congenital, (Gardner syndrome) or related to endocrine disorders, chronic inflammatory processes, or traumas. In this work, the authors wanted to illustrate the correlation between the presence of multiple osteomas in the craniofacial skeleton and Gardner syndrome to underscore the importance of the role of the oral surgeon in the early identification of this pathology. Malignant evolution of intestinal lesions arising from Gardner syndrome can be avoided if diagnosed in an early stage. Two significant clinical cases are described and discussed. In the first one, a diagnosis of Gardner syndrome was made after colonoscopy.
骨瘤是良性的缓慢生长的肿瘤。这些病变主要局限于颅面骨骼，很少在其他骨骼中诊断出来。病因通常是多因素的。它可能是遗传的或先天性的（ Gardner 综合征），或与内分泌紊乱、慢性炎症过程或创伤有关。在这项工作中，作者们希望说明颅面骨骼中多发性骨瘤的存在与 Gardner 综合征之间的相关性，以强调口腔外科医生在早期识别这种病理的重要性。如果在早期诊断，可避免源自 Gardner 综合征的肠道病变的恶性演变。描述并讨论了两个重要的临床病例。在第一个病例中，在结肠镜检查后做出了 Gardner 综合征的诊断。
