Starch-Jensen Thomas
Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark.
Open Dent J. 2017 Feb 28;11:120-125. doi: 10.2174/1874210601711010120. eCollection 2017.
Osteoma is a benign slow-growing osteogenic neoplasm commonly occurring in the craniofacial skeleton, characterized by the proliferation of compact and/or cancellous bone. Osteomas may be peripheral, central, or extraskeletal. Peripheral osteomas arise from the periosteum and are quite uncommon in the jaw bones. The exact aetiology and pathogenesis of peripheral osteoma are unknown. Clinically, peripheral osteomas are usually asymptomatic, but depending on the location and size of the lesion, it may cause swelling, pain, esthetic disfigurement and functional impairment. On radiological imaging, a peripheral osteoma appears often as well-circumscribed, round to oval, pedunculated radiopaque mass attached to the cortex by a broad base or a pedicle. Asymptomatic osteomas are treated conservatively, while surgical excision is indicated when the lesion is symptomatic, actively growing, or for cosmetic reasons. Histologically, osteomas are composed of a normal-appearing, dense mass of lamellar bone. Recurrence of peripheral osteoma after surgical removal is extremely rare and there are no reports of malignant transformation. A review of the literature disclosed only 7 well-documented cases of peripheral osteoma located at the zygomatic bone. The purpose of this article is to present the clinical, radiographic, surgical and histological features of a solitary peripheral osteoma of the left zygomatic arch in a 55-year-old woman and to review the literature about this uncommon pathologic entity.
骨瘤是一种常见于颅面骨骼的良性、生长缓慢的成骨性肿瘤,其特征是密质骨和/或松质骨增生。骨瘤可分为外周型、中心型或骨外型。外周型骨瘤起源于骨膜,在颌骨中较为罕见。外周型骨瘤的确切病因和发病机制尚不清楚。临床上,外周型骨瘤通常无症状,但根据病变的位置和大小,可能会引起肿胀、疼痛、美观受损和功能障碍。在放射影像学上,外周型骨瘤通常表现为边界清晰、圆形至椭圆形、带蒂的不透射线肿块,通过宽基底或蒂附着于皮质。无症状的骨瘤采用保守治疗,而当病变有症状、生长活跃或出于美容原因时,则需手术切除。组织学上,骨瘤由外观正常的致密板层骨组成。外周型骨瘤手术切除后复发极为罕见,也没有恶变的报道。文献综述仅发现7例记录完整的位于颧骨的外周型骨瘤病例。本文旨在介绍一名55岁女性左颧弓孤立性外周型骨瘤的临床、影像学、手术和组织学特征,并回顾有关这种罕见病理实体的文献。