Oguike J U, Emeruwa A C
Department of Microbiology, University of Nigeria, Nsukka Campus, Anambra State.
Microbiologica. 1990 Jul;13(3):267-71.
Stool specimens collected from 320 infants under 5 years of age resident in both rural and urban centres of Nsukka and Enugu towns in Anambra State, Nigeria were examined for the presence of Clostridium difficile and the frequency of occurrence determined. Clostridium difficile was isolated from 156 out of 320 samples (48.8%). The frequency was higher in infants resident in rural areas (52.5-48.3%) than in their urban counterparts (47.8-42%). A high frequency rate (77%) was obtained in diarrheal cases as against 42% in non diarrheal cases. A frequency of 57.7% was obtained in infants in the age group of 1 day - 1 yr, which decline with age to the lowest 5.6% in the age group of 4.5 years. The frequency of 66.1% was obtained in infants breast-fed plus formula supplementation, 41.7% in infants exclusively breast-fed and 33% in infants fed exclusively with formula foods. The findings suggest that the type of living environments, together with age and mode of feeding may contribute to the high intestinal carriage of Clostridium difficile in infants in parts of Nigeria.
对来自尼日利亚阿南布拉州Nsukka和Enugu镇城乡中心的320名5岁以下婴儿采集的粪便样本进行检测，以确定是否存在艰难梭菌并确定其发生频率。在320个样本中，有156个分离出了艰难梭菌（48.8%）。农村地区婴儿的发生率（52.5%-48.3%）高于城市地区的婴儿（47.8%-42%）。腹泻病例的发生率较高（77%），而非腹泻病例为42%。1日龄至1岁年龄组婴儿的发生率为57.7%，随着年龄增长发生率下降，4.5岁年龄组最低，为5.6%。母乳喂养加配方奶补充喂养的婴儿发生率为66.1%，纯母乳喂养的婴儿为41.7%，纯配方奶喂养的婴儿为33%。研究结果表明，生活环境类型以及年龄和喂养方式可能导致尼日利亚部分地区婴儿肠道艰难梭菌携带率较高。
