Jiménez-Cohl Pedro, Earle Nicholas M, González Beltrán R, Thieck Elfride J
Servicio de Neurología y Unidad de Estudios Autonómicos, Hospital Militar de Santiago, Chile.
Rev Med Chil. 2012 Feb;140(2):145-52. doi: 10.4067/S0034-98872012000200001.
Patients with postural orthostatic tachycardia syndrome (POTS) report dizziness, lightheadedness, weakness, blurred vision, and fatigue upon standing. The diagnosis of the syndrome is made when an orthostatic intolerance and tachycardia appear in the standing position.
To report 15 patients with POTS.
Review of Tilt test reports in a period of 15 years. Those reports in which orthostatic postural tachycardia and symptoms compatible with POTS appeared, were selected for analysis.
We identified 15 patients (3.1% of all positive Tilt test reports) with compatible signs and symptoms. There was a lag of 8 -10 years between the onset of symptoms and the time of diagnosis. Most patients complained of orthostatic intolerance, dizziness and frequent fainting. Orthostatic tachycardia and symptoms occurred on average after 2.9 and 6.1 minutes, respectively,of staying in the standing position. These patients had a high frequency of family history of syncope orpresyncope (66% frequency) and hyper mobility syndrome (53% prevalence). Only 33% of the patients reported relief of their symptoms after being treated (most of them with fludrocortisone). Most patients that reported little or no relief, did not use medications or were treated for a short period.
POTS syndrome is uncommon but disturbs quality of life of those who suffer it. Its association with hyper mobility syndromes must be investigated.
体位性直立性心动过速综合征（POTS）患者在站立时会出现头晕、眩晕、虚弱、视力模糊和疲劳等症状。当直立不耐受和心动过速出现在站立位时，即可诊断该综合征。
报告15例POTS患者。
回顾15年期间的倾斜试验报告。选择那些出现直立性姿势性心动过速及与POTS相符症状的报告进行分析。
我们确定了15例有相符体征和症状的患者（占所有阳性倾斜试验报告的3.1%）。症状出现与诊断时间之间有8至10年的间隔。大多数患者主诉直立不耐受、头晕和频繁昏厥。直立性心动过速和症状分别平均出现在站立2.9分钟和6.1分钟后。这些患者晕厥或接近晕厥家族史的发生率较高（66%），高柔韧性综合征的患病率较高（53%）。只有33%的患者在接受治疗后症状有所缓解（大多数使用氟氢可的松治疗）。大多数报告症状缓解很少或没有缓解的患者，未使用药物治疗或治疗时间较短。
POTS综合征并不常见，但会干扰患者的生活质量。必须对其与高柔韧性综合征的关联进行研究。
