连接蛋白和间隙连接蛋白的翻译后修饰。
Posttranslational modifications in connexins and pannexins.
机构信息
Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
出版信息
J Membr Biol. 2012 Jun;245(5-6):319-32. doi: 10.1007/s00232-012-9453-3. Epub 2012 Jun 28.
Abstract
Posttranslational modification is a common cellular process that is used by cells to ensure a particular protein function. This can happen in a variety of ways, e.g., from the addition of phosphates or sugar residues to a particular amino acid, ensuring proper protein life cycle and function. In this review, we assess the evidence for ubiquitination, glycosylation, phosphorylation, S-nitrosylation as well as other modifications in connexins and pannexin proteins. Based on the literature, we find that posttranslational modifications are an important component of connexin and pannexin regulation.
摘要
翻译后
翻译后内容
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